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Description
Activin A Protein, Human/Mouse/Rat (High Active）Product Specification Synonyms Inhibin beta A chain,Activin beta A chain,Erythroid differentiation protein (EDF), Accession P08476 Amino Acid Sequence Gly311 Ser426, F368A Expression System E. coli Molecular Weight 14 kDa (Reducing) Purity >95% by SDS PAGE and HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer 4mM HCl Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in
Product Specification
| Synonyms | Inhibin beta A chain,Activin beta-A chain,Erythroid differentiation protein (EDF), |
| Accession | P08476 |
| Amino Acid Sequence | Gly311-Ser426, F368A |
| Expression System | E.coli |
| Molecular Weight | 14 kDa (Reducing) |
| Purity | >95% by SDS-PAGE and HPLC. |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | 4mM HCl |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in reconstitution buffer (4mM HCl) after rapid centrifugation. |
| Stability & Storage | ·12 months from date of receipt, -20 to -70 °C as supplied. |
| Reference | Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16239-44. |
Background
Activin A is a dimeric glycoprotein belonging to the transforming growth factor-beta (TGF-β) superfamily of cytokines. It is involved in various biological processes, including embryonic development, reproductive function, and regulation of the immune system. Activin A is produced by a wide range of cell types, including immune cells, endothelial cells, and reproductive tissues. It exerts its effects by binding to the activin type II receptors, leading to the activation of downstream signaling pathways involved in cell proliferation, differentiation, and immune modulation. Activin A has been implicated in the regulation of inflammation, tissue repair, and the pathogenesis of various diseases, including cancer and autoimmune disorders.
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