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Description
Dicer Recombinant Rabbit mAb (S-2497-202)Product Specification Host Rabbit Antigen Dicer Synonyms Endoribonuclease Dicer; Helicase with RNase motif (Helicase MOI); DICER; HERNA; KIAA0928; DICER1 Immunogen Recombinant Protein Location Cytoplasm Accession Q9UPY3 Clone Number S 2497 202 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu, Ms, Rt Predicted Reactivity Bv, Ck, Hm, Xe Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance
Product Specification
| Host | Rabbit |
| Antigen | Dicer |
| Synonyms | Endoribonuclease Dicer; Helicase with RNase motif (Helicase MOI); DICER; HERNA; KIAA0928; DICER1 |
| Immunogen | Recombinant Protein |
| Location | Cytoplasm |
| Accession | Q9UPY3 |
| Clone Number | S-2497-202 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Bv, Ck, Hm, Xe |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt |
Background
Dicer is a multidomain RNase III enzyme that recognizes double-stranded RNA (dsRNA) or short-hairpin RNA (shRNA), measures ~22 nt from the 3′ overhang, and cleaves both strands to generate small interfering RNAs or microRNAs bearing 2-nt 3′ overhangs; these products are then loaded into Argonaute to form the RNA-induced silencing complex that drives gene silencing, making Dicer the central processor of the RNA interference pathway essential for development, viral defense, and genome stability.
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Exchange/Return Notes
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