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Description
Galectin-4 Protein, HumanProduct Specification Species Human Synonyms Antigen NY CO 27, GAL4, gal 4, galectin 4, Galectin4, L 36 lactose binding protein, L36LBP, Lactose binding lectin 4, lectin galactoside binding soluble 4, LGALS4 Accession P56470 Amino Acid Sequence Ala2 Ile323 Expression System E. coli Molecular Weight 36kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Physical Appearance Lyophilized Powder Storage Buffer 250mM Tris, 150mM NaCl,
Product Specification
| Species | Human |
| Synonyms | Antigen NY-CO-27, GAL4, gal-4, galectin 4, Galectin4, L-36 lactose-binding protein, L36LBP, Lactose-binding lectin 4, lectin galactoside-binding soluble 4, LGALS4 |
| Accession | P56470 |
| Amino Acid Sequence | Ala2-Ile323 |
| Expression System | E.coli |
| Molecular Weight | 36kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 250mM Tris, 150mM NaCl, 3mM DTT, pH8.0 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Poland P A. et al. (2022) Cloning, Expression, and Purification of Galectins for In Vitro Studies. Methods in Molecular Biology. 2442: 41-54. 2、Rustiguel J K. et al. (2016) Recombinant expression, purification and preliminary biophysical and structural studies of C-terminal carbohydrate recognition domain from human galectin-4. 118: 39-48. 3、Stancic M. et al. (2012) Galectin-4, a Novel Neuronal Regulator of Myelination. GLIA. 60(6): 919-935. |
Background
Galectins are best known for their ability to bind glycoconjugates containing β-galactose, but classification of these small proteins within the galectin family is also defined by amino acid homology within structural domains and exon/intron junctions within genes. Galectin-4 (Gal4), a tandem-repeat type galectin, is expressed in healthy epithelium of the gastrointestinal tract. Altered levels of Gal4 expression are associated with different types of cancer, suggesting its usage as a diagnostic marker as well as target for drug development. The functional data available for this class of proteins suggest that the wide spectrum of cellular activities reported for Gal4 relies on distinct glycan specificity and structural characteristics of its two carbohydrate recognition domains. Gal4, a tandem-repeat-type lectin with affinity to sulfatide and non-sialylated termini of N-glycans, has the ability to regulate adhesion of cells to ECM components and is also involved in polarized membrane trafficking.
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4.5 ★★★★★
Based on 5 reviews
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Product Reviews
★★★★★ 5
Squeaks and glows
Style: Recharges, Size: Medium
Squeaks. Glows, and labs love them.
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Reviewed in the United States on January 19, 2026
★★★★★ 3
good but no glow
Style: Recharges, Size: Medium
good ball but as others say, the glow in the dark really isn't there.
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Reviewed in the United States on May 14, 2026
★★★★★ 5
Good grip glow ball
Style: Recharges, Size: Medium
Love this glow in the dark Chuck IT. Get a black light flashlight to charge the neon instantly. Good texture gives the dog better grip than the smooth all white glow in the dark chuck it balls.
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Reviewed in the United States on January 9, 2026
★★★★★ 5
Our German Sheppard loves these
Size: Medium
These cost a bit more than tennis balls, but they are so much nicer and longer lasting. For starters, they stay cleaner than tennis balls because they’re smooth rubber. Dirt won’t build up on them and if anything does stick, like grass or soil, it falls off once the dog slobber dries. They’re also thick, so they don’t fall apart or blow out like a normal tennis ball does in our dog’s jaws after 30 seconds. Our GS chomps on these like crazy and the only damage they’ve suffered is a crack that developed from the edge of the hole, but the crack is growing very slowly and none of these balls have totally failed yet. The balls do whistle when thrown ant high speed and that may help a dog track and locate it, but I’m not sure. Our neighbors hear the whistling too so it’s far from silent. Lastly the orange ball is easy to locate out in our yard, but the dark blue practically disappears.
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Reviewed in the United States on April 6, 2025
★★★★★ 5
Great for smaller dogs
Size: Small
These two balls are perfect for the smaller mouthed dog that loves to play fetch.
These balls are not only super durable (lots of teeth biting), but float in the baby pool we use for our miniature dachshunds.
The value here is much better than you’d find anywhere else. The noise, if bitten hard enough, was “low” at best. Easy to spot/find if overthrown. Will definitely buy again once these are in bad repair; so far, so good-love these for my fur babies!
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Reviewed in the United States on October 8, 2024