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Description
FABP1 His Tag, HumanProduct Specification Species Human Synonyms LFABP Accession P07148 Amino Acid Sequence Met1 Ile127, with N terminal 8*His MHHHHHHHHMSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI Expression System E. coli Molecular Weight 16kDa (Reducing) Purity 95% by SDS PAG E& RP HPLC Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder
Product Specification
| Species | Human |
| Synonyms | LFABP |
| Accession | P07148 |
| Amino Acid Sequence | Met1-Ile127, with N-terminal 8*His MHHHHHHHHMSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI |
| Expression System | E.coli |
| Molecular Weight | 16kDa (Reducing) |
| Purity | ＞95% by SDS-PAG E& RP-HPLC |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
FABP1 (LFABP) has been initially characterised in the liver (thus its name) but is also expressed in small intestine (duodenum and jejunum). FABP1 appears to be the most promiscuous FABP as it was reported to bind a variety of small molecules in addition to fatty acids including bile acids, lysophosphatidic acid, prostaglandins, fatty acyl-CoA, bilirubin and heme. FABP1 is a PPARα target gene. While some studies suggested that FABP1 might be involved in the delivery of ligands for PPARα activation in the nucleus, FABP1-deficient mice showed normal regulation of PPARα target genes regulation. FABP1 was reported to enhance apoB-lipoprotein secretion, which would suggest involvement of this protein in the delivery of fatty acids to the ER for esterification into lipoprotein-destined TG. Hepatic fatty acid oxidation is also diminished in fasted FABP1 knockout mice, which implies deficient transport of fatty acids to the oxidative pathway. Interestingly, no accumulation of intracellular TG accompanied attenuation of fatty acid oxidation even when the mice were challenged with a high-fat diet.
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4.4 ★★★★★
Based on 12 reviews
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Product Reviews
★★★★★ 4
Cute but very inexpensive
Keep in mind you get what you pay for. That said, this is a very cute watch and my granddaughter loves it. It was a Christmas gift and when she first opened it and set it, it would not run. Later, when I was working on requesting an exchange, I noticed it was running. Hopefully it will continue to run and she will be happy with this watch. It's a unique style and perfect for a teenage girl.
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Reviewed in the United States on December 31, 2025
★★★★★ 5
perfect fit!!
This watch is reliable & breaks in nicely for a comfortable fit
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Reviewed in the United States on February 21, 2024
★★★★★ 1
Pretty but leather is mildewed.
I read the reviews but took a chance that the one I received would not smell mildewed. Oh my!! It stinks to high heaven!!! And it is too small for my wrist…another chance I took.
Instead of returning it, I’m going to try and replicate it using the watch and dangles with ribbon and cords.
It was wrapped very tightly in bubble wrap. Perhaps the leather would not have mildewed if it had been able to breathe. Boy! Does it stink!!!!!
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Reviewed in the United States on September 29, 2025
★★★★★ 3
Snap closure watch.
Not the best quality or materials but remember, it’s extremely inexpensive.
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Reviewed in the United States on September 8, 2025
★★★★★ 5
Nice accessory for anyone to wear, goes well with any style
Durable material makes it easy to slip onto any wrist (plus, adjustable strap, so there's that too). The fact that the watch actually WORKS is an added point, considering most of these out there have the clock as a graphical enhancement rather than an actual working point to the piece.
The title of the item says for girls, but whoever you are out there, wear it despite what it says. These sorts of accessories are multi-person usage. It looks cool with any outfit design, too.
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Reviewed in the United States on November 26, 2023
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