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Description
Alexa Fluor® 488 Mouse Anti-Human IL-17A Antibody (S-3341)Product Specification Host Mouse Antigen IL 17A Synonyms Interleukin 17A; IL 17; Cytotoxic T lymphocyte associated antigen 8 (CTLA 8); CTLA8; IL17; IL17A Location Secreted Accession Q16552 Clone Number S 3341 Antibody Type Mouse mAb Isotype IgG1,k Application ICFCM Reactivity Hu Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12
Product Specification
| Host | Mouse |
| Antigen | IL-17A |
| Synonyms | Interleukin-17A; IL-17; Cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8); CTLA8; IL17; IL17A |
| Location | Secreted |
| Accession | Q16552 |
| Clone Number | S-3341 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | ICFCM |
| Reactivity | Hu |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| ICFCM | 5μl per million cells in 100μl volume | Hu |
Background
IL-17A is a 155-amino-acid, disulfide-linked homodimeric pro-inflammatory cytokine secreted primarily by Th17 cells, γδ T cells and innate lymphoid cells; it engages the ubiquitously expressed IL-17RA/RC receptor complex to trigger TRAF6- and Act1-dependent signaling cascades that activate NF-κB, MAPKs and C/EBP transcription factors, thereby inducing massive release of neutrophil-mobilizing chemokines (CXCL1, CXCL8), G-CSF, IL-6 and antimicrobial peptides, orchestrating granulopoiesis, extracellular-matrix remodeling and barrier immunity; dysregulated IL-17A underlies autoimmune pathologies such as psoriasis, ankylosing spondylitis and multiple sclerosis, making it the target of FDA-approved biologics like secukinumab and ixekizumab.
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4.6 ★★★★★
Based on 29 reviews
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Product Reviews
★★★★★ 5
Beyond my expectations…
Scent: Incredible 10/10. The entire shower smells like a spa afterwards. Woody notes, vanilla scent is deliciously heavy and warm, and even one pump delivers a punch of fresh vanilla scent to your entire body. I’m a woman who is in love with heavy earthy scents and this is it!
P.S it also matches well with scents like vanilla, cocoa butter, chocolate, or even delicious “smore” scents! I pair it with vanilla and cocoa butter scented deodorant, vanilla perfume, or vanilla body lotion and it works amazing!
Longevity: Lasts the entire day if I’m staying home just relaxing, not working out or sweating very much. I could shower in the early morning and by the time my head hits the pillow I still smell it faintly!
If I’m out and about it still lasts hours I’d estimate around 6-8 hours before the scent fades! If I shower at 6am, come home at 5pm-6pm after work I still smell fresh! (I always shower 2x a day but you don’t even need to with this!
Value for Money/Size: Oh absolutely! I think I bought this soap two weeks ago? Used it nearly every day, and you can’t even tell! One pump is enough, two pumps MAX per shower per day.
I decided to lavish myself by buying this soap, because it’s a bit more pricey. But it’s actually saving me more money, at this rate I’ll be buying another one of these every 3 months! So that’s…4 times a year? 5 max? That’s incredible. I’ll probably stick with Cremo for life honestly. And I’m a woman!💕🎀
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 7, 2026
★★★★★ 5
High Quality and Smells Great!
This is so far superior to the standard soaps that you buy off the shelf in a supermarket. It creates a truly luxurious lather and smells fantastic without being obnoxious or perfume.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 10, 2026
★★★★★ 5
Best vanilla body wash I've seen
Proper vanilla scent with a kick, without the vomit inducing synthetic aftertaste
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 26, 2026
★★★★★ 5
Pastorally edifying & personally encouraging
Format: Kindle
As a pastor and a biblical counselor, I’ve read Powlison many times. I know people who knew him personally. He is a man of nearly mythic proportions in the 2026 landscapes of biblical counseling.
And so, based the current landscape of the BC movement at the dawn of 2026, I thought it was to revisit Powlison myself.
This is an excellent little read. Recommended for ALL pastors and counselors.
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Reviewed in the United States on January 25, 2026
★★★★★ 4
Insightful, Bibical, and Helpful, but with One Major Oversimplification
Format: Paperback
This brief book posthumously publishes new reflections from David Powlison about pastoral counseling. The book opens with a foreword from Ed Welch, who writes about his personal connection with the author and the ways that this book has sharpened his thinking, and the main text includes an introduction, two chapters, and an appendix with suggested reading from both Christian and secular sources. Although "The Pastor as Counselor: The Call for Soul Care" is only eighty pages long, it is full of articulate, biblical, and concise reflections about what counseling is and why pastoral counseling is so uniquely powerful.
Insightful and Wise
Although I read this book from a layperson's perspective, I found it insightful and helpful. Powlison explains that pastors are always counselors, regardless whether or not they meet one-on-one with people, and show by example what kind of soul care they think is necessary for flourishing. He encourages pastors to take stock of how they present themselves and what common failings they need to avoid, such as offering platitudes or not listening well. He also delineates the clear differences between pastoral counseling and secular "therapeutic professionalism." He explains that because pastoral counseling is gospel-based and flows out of a personal relationship that is free from clinical detachment or professional reserve, it can be particularly powerful to help change people's lives.
One Concern
I absolutely agree with this, but unfortunately, Powlison creates a false dichotomy between biblical counseling and professional therapy, making it sound like all resources outside of the church will be unhelpful and spiritually destructive. The church has unique resources to meet sufferers' needs, and we shouldn't abandon Christians to the spiritually twisted and harmful ideas common within secular counseling, but Powlison creates a false dilemma between abandoning people to godless counseling versus taking on all of their care within the church directly. He does not address how Christian mental health professionals can support the church's work in complicated cases, and does not indicate what a pastor should do if someone's mental health situation or life struggles are beyond the church's understanding or ability to deal with.
Because I am not very familiar with Powlisons's work, I do not know what all of his views are related to integrative approaches to counseling, and it is possible that he has addressed this issue in-depth elsewhere. I certainly did not expect him to cover it in much detail in this very short book, but the oversimplification that he presents calls for discernment and additional reading. I hope that Powlison's writing here will not make pastors resistant to partnering with professionals outside of the church body, as long as those therapists bring a Christian worldview and gospel implications into each aspect of their work.
Conclusion
Despite my concerns about this oversimplified element, I would strongly recommend that pastors read this book as a way to evaluate themselves, better understand their unique role in people's lives, and consider how they can better care for others in their context. Powlison addresses many issues very well in this book, and it is a wonderful resource for pastors who need succinct, encouraging insight into how they can better understand the counseling aspect of their pastoral role and engage in meaningful conversations, caring relationships, and one-on-one care.
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Reviewed in the United States on June 30, 2021
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