Pay in installments of $62.50 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 28 - Sep 2
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Human & Monkey PCSK9 OneStep ELISA KitProduct Specification Antigen PCSK9 Immunogen Recombinant Protein Antibody Type Recombinant mAb Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8'C as supplied. Kit Precision Intra assay: 4. 3% Inter assay: 5. 2% Sample type Cell culture supernatant, Serum, Plasma Assay type Sandwich (quantitative) Sensitivity 11. 177 pg ml Range 31. 25 pg mL 2000 pg mL Recovery Cell culture supernatant: 85% Serum: 100%
Product Specification
| Antigen | PCSK9 |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Purification | Protein A |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8'C as supplied. |
Kit
| Precision | Intra-assay: 4.3%； Inter-assay: 5.2% |
| Sample type | Cell culture supernatant, Serum, Plasma |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 11.177 pg/ml |
| Range | 31.25 pg/mL – 2000 pg/mL |
| Recovery | Cell culture supernatant: 85% Serum: 100% Plasma: 87% |
| Assay time | 60 minutes |
| Species reactivity | Human; Monkey |
Background
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key regulator of cholesterol metabolism, primarily known for its role in degrading low-density lipoprotein receptors (LDLR) in the liver. By binding to LDLR and promoting its lysosomal degradation, PCSK9 reduces the liver's ability to clear circulating LDL cholesterol (LDL-C), leading to elevated plasma LDL-C levels. Gain-of-function mutations in the PCSK9 gene are associated with autosomal dominant hypercholesterolemia, while loss-of-function variants correlate with reduced LDL-C and cardiovascular risk.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy