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Description
Nucleoprotein His tag, HRSVB (Strain 18537)Product Specification Species HRSV Synonyms Nucleoprotein, Protein N, Nucleocapsid protein Accession P24566 Amino Acid Sequence Met1 Leu391, with N terminal 8*His
Product Specification
| Species | HRSV |
| Synonyms | Nucleoprotein, Protein N, Nucleocapsid protein |
| Accession | P24566 |
| Amino Acid Sequence | Met1-Leu391, with N-terminal 8*His MHHHHHHHHMALSKVKLNDTLNKDQLLSSSKYTIQRSTGDNIDTPNYDVQKHLNKLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTIKILKDAGYHVKANGVDITTYRQDINGKEMKFEVLTLSSLTSEIQVNIEIESRKSYKKLLKEMGEVAPEYRHDSPDCGMIILCIAALVITKLAAGDRSGLTAVIRRANNVLKNEIKRYKGLIPKDIANSFYEVFEKHPHLIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGSGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPNFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAAKAYAEQLKENGVINYSVLDLTAEELEAIKHQLNPKEDDVEL |
| Expression System | E.coli |
| Molecular Weight | 43kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM PB, 150mM NaCl, 1mM EDTA, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Oliveira A P. et al. (2013) Human respiratory syncytial virus N, P and M protein interactions in HEK-293T cells. Virus Res. 177(1): 108-112. 2、Céspedes P F. et al. (2014) Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells. Proc Natl Acad Sci U S A. 111(31): E3214. |
Background
Human Respiratory Syncytial Virus (HRSV) is a negative-sense single-stranded RNA virus that belongs to the Paramyxoviridae family and the Pneumovirinae subfamily, and considered the most important pathogen causing respiratory disease in infants and neonates worldwide. The nucleoprotein of HRSV, a canonical cytosolic protein, is highly conserved among pneumoviruses and interacts with viral RNA, generating a helicoidal nucleocapsid which is responsible for genome and anti-genome resistance to RNase. In addition, the nucleoprotein could be responsible for inhibiting T-cell activation during infection by HRSV, and expressed on the surface of epithelial and dendritic cells, preventing immunological synapse assembly by naïve CD4+ T cells. Therefore, this protein is defined as a major virulence factor that contributes to impairing acquired immunity and enhances susceptibility to reinfection by HRSV.
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4.4 ★★★★★
Based on 9 reviews
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Product Reviews
★★★★★ 5
Great quality and Easy to install
Size: 18-22 Accord
As someone with zero experience changing air filters, I was honestly surprised at how easy this was. The fit was perfect for my 2010 Honda Accord Sport, and both the cabin and engine air filters installed with no issues at all. It even came with clear, easy-to-follow instructions that made the whole process stress-free. Saved myself money from going to the dealership, and my car is running great. Definitely recommend for beginners wanting to do a simple DIY maintenance job.
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Reviewed in the United States on May 25, 2026
★★★★★ 5
Great Product Great Price
Size: 16-21 Civic, 17-22 CR-V
product was a good priced. Fit as it should. will buy again when needed.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 28, 2026
★★★★★ 5
Air filters are great
Size: 10-24 4RUNNER, 10-23 GX460
I received when promised and it fit my automobile correctly, I get good gas mileage already so we will see if the gas mileage comes up. The quality was great always looking for high quality when changing the air filters and this item met that standard. Go ahead and buy it will meet you demands.
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Reviewed in the United States on May 24, 2026
★★★★★ 4
Great value
Size: 18-26 Expedition, 15-26 F-150, 18-26 Navigator
The engine air filter fit perfect. The cabin air filter was a bit of a challenge fitting. seemed to be a bit larger but it went in and got the cap back on the box. For the price you cant beat it. Would buy again!
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Reviewed in the United States on May 15, 2026
★★★★★ 5
Great Filter Set for Allergy‑Sensitive Families and MPG‑Minded Drivers
Size: 21-25 TLX, 18-25 Odyssey
I bought this set because I prefer handling routine maintenance myself, especially cabin and engine air filters, rather than paying dealership prices for simple jobs. The package included one cabin air filter and one engine air filter, plus a full backup set for the next service interval.
Both filters installed easily and fit the 2018 Honda Odyssey exactly as expected. No trimming, no forcing, and no alignment issues. The cabin filter seated cleanly in the glove‑box housing, and the engine filter dropped into the airbox without any airflow restriction or sealing gaps.
This setup is ideal for Odyssey owners who want to maintain optimal cabin air quality—especially helpful for families with allergies—and for drivers looking to keep engine airflow unrestricted for the best possible MPG and throttle response. It may not be necessary for anyone who relies exclusively on dealership service or doesn’t perform their own maintenance.
Overall, this is a straightforward, high‑value filter set that installs cleanly and supports both air quality and engine efficiency for DIY‑minded Odyssey owners.
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Reviewed in the United States on May 26, 2026
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