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Description
Glutamine Synthetase (GS) Recombinant Rabbit mAb (SDT-549-25)Product Specification Host Rabbit Antigen Glutamine Synthetase (GS) Synonyms Glutamate ammonia ligase, Palmitoyltransferase GLUL, GLUL, GLNS Immunogen Synthetic Peptide Location Cytoplasm, Cell membrane Accession P15104 Clone Number SDT 549 25 Antibody Type Recombinant mAb Application WB, IHC P Reactivity Hu, Ms, Rt Predicted Reactivity Fs, Mq, Av, Pg, Hm, Dg, Bv Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Antigen | Glutamine Synthetase (GS) |
| Synonyms | Glutamate--ammonia ligase, Palmitoyltransferase GLUL, GLUL, GLNS |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Cell membrane |
| Accession | P15104 |
| Clone Number | SDT-549-25 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Fs, Mq, Av, Pg, Hm, Dg, Bv |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 | |
| IHC | 1:500 |
Background
Glutamine synthetase (GS) is a 42 kDa protein. GS converts glutamate and ammonia into glutamine using adenosine triphosphate (ATP). GS exerts critical biological functions in liver, kidney, skeletal muscle, and brain. In cancer, GS plays a pivotal role in restructuring the cell metabolism in order to enable continued proliferation and survival of malignant cells in poorly vascularized and nutrient-deprived environments. GS usually combines with Glypican and HSP70 for differentiated diagnosis of liver hypoperia nodules and hepatocellular carcinoma.
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