SKU: 23221743865

PE-Cy7 Armenian hamster Anti-Mouse/Rat CD61 Antibody (S-R656)

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Description

PE-Cy7 Armenian hamster Anti-Mouse/Rat CD61 Antibody (S-R656)Product Specification Host Armenian hamster Antigen CD61 Synonyms Integrin beta 3; Platelet membrane glycoprotein IIIa (GPIIIa); Itgb3 Location Cell membrane, Synapse Accession O54890 Clone Number S R656 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms, Rt Positive Sample C57BL 6 mouse bone marrow Purification Protein G Concentration 0. 2 mg ml Conjugation PE Cy7 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3%

Product Specification


Host Armenian hamster
Antigen CD61
Synonyms Integrin beta-3; Platelet membrane glycoprotein IIIa (GPIIIa); Itgb3
Location Cell membrane, Synapse
Accession O54890
Clone Number S-R656
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms, Rt
Positive Sample C57BL/6 mouse bone marrow
Purification Protein G
Concentration 0.2 mg/ml
Conjugation PE-Cy7
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1.25μl per million cells in 100μl volume Ms, Rt

Background

CD61, also known as integrin β3, is a 90-92 kDa type I transmembrane glycoprotein that dimerizes with integrin αIIb (CD41) to form the platelet fibrinogen receptor GPIIb/IIIa or with integrin αV (CD51) to form the vitronectin receptor, and plays a pivotal role in platelet aggregation, clot retraction, angiogenesis, and the adhesion and migration of osteoclasts, smooth muscle cells and tumor cells via recognition of RGD motifs in ligands such as fibrinogen, fibronectin, von Willebrand factor, vitronectin and thrombospondin.

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Exchange/Return Notes
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SKU: 23221743865

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Reviewed in the United States on November 3, 2021
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★★★★★ 1
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