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Description
PIN1 Recombinant Rabbit mAb (S-2731-43)Product Specification Host Rabbit Antigen PIN1 Synonyms Peptidyl prolyl cis trans isomerase NIMA interacting 1; Peptidyl prolyl cis trans isomerase Pin1 (PPIase Pin1); Rotamase Pin1 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession Q13526 Clone Number S 2731 43 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu, Ms, Rt, Mk Positive Sample HEK 293, Jurkat, A549, HeLa, NIH 3T3, mouse heart, PC 12, rat brain, COS
Product Specification
| Host | Rabbit |
| Antigen | PIN1 |
| Synonyms | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1 (PPIase Pin1); Rotamase Pin1 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | Q13526 |
| Clone Number | S-2731-43 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC |
| Reactivity | Hu, Ms, Rt, Mk |
| Positive Sample | HEK-293, Jurkat, A549, HeLa, NIH/3T3, mouse heart, PC-12, rat brain, COS-7 |
| Predicted Reactivity | Bv |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:2000 | Hu, Ms, Rt, Mk |
| ICC | 1:500 | Hu |
Background
PIN1 is a conserved 163-residue peptidyl-prolyl cis-trans isomerase composed of an N-terminal WW domain and a C-terminal catalytic PPIase domain, both recognizing pSer/Thr-Pro motifs; by selectively isomerizing these phosphorylated bonds it acts as a post-phosphorylation switch that reshapes the conformation, stability, localization and ubiquitination of hundreds of client proteins—ranging from p53 and cyclins to NF-κB and APP—thereby governing cell-cycle progression, transcription, immune signaling and neuronal homeostasis, while its frequent over-activation in cancer drives oncogenic pathways and its loss contributes to neurodegenerative diseases such as Alzheimer’s.
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4.3 ★★★★★
Based on 22 reviews
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Product Reviews
★★★★★ 5
Price
Size: 50 sqft
Priced well . Good quality
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Reviewed in the United States on February 26, 2026
★★★★★ 5
Accurate size.
Size: 50 sqft
item as descibed
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Reviewed in the United States on February 21, 2026
★★★★★ 5
Reduce sound vibrations in your car! Works great! This is not sound proofing, it is Sound Deadening
Size: 10 sqft, Size: 10 sqft
This Butyl rubber sound proofing kit includes nine 15 1/2" x 10" peel and stick panels. It really is a lot of coverage, but I still will need a second box to finish my car doors. The instructions are easy to follow and the only tools you need are scissors or a knife and a small roller, but you could get away with using a pan scraper to press the product down. You may need paper and a pen to make a template for certain areas, though. I used some cardboard from my recycle bin to cut template pieces for the hard to see areas inside my doors. This is fairly easy to install once you have it cut into pieces, just peel the backing off and stick it on. Be very careful to not let it stick to itself, as it will be nearly impossible to separate. This stuff is crazy sticky! No worries about it coming off once you've stuck it to your car.
To add this to your car doors, you will have to remove the interior door panels, but there are lots of YouTube videos on how to do this on all sorts of cars.
Note that is is sound deadening material - Not sound proofing! You do not need to cover 100% of the car with this. The material is designed to stop noise from resonating through metals, so even one piece of this on a large area of sheet metal will stop the sound vibrations quite a bit. I am covering about 80% of my car doors with it, then planning to put sound proofing on top of it. This sound deadening material needs to come in contact with the metal surfaces to stop the sound vibrations, so it would not be very helpful to put it on top of sound proofing material.
Also note that the installation requires temperatures above 50° Fahrenheit. Since it is winter, I've warmed up my garage while working on this project. In low temps, the sticky stuff would probably have trouble adhering to cold metals. So far I have tested just having it on my front doors, but I already can hear the difference. This soundproofing definitely does minimize road noise and external sounds from getting inside your car. It also stops music vibrations, so my radio now sounds clearer than it did before. I don't plan to pull out my vehicle carpet to install on the floor, but I would imagine that if I did it would greatly reduce the road noise even more.
Definitely five stars on this product!
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Reviewed in the United States on January 17, 2026
★★★★★ 5
Quality mats that provide noticeable noise suppression
Size: 10 sqft
I used these mats when I replaced the carpet in my Chevy Tahoe. Cutting the mats to size was easy enough with a utility knife and a straightedge. The adhesive backing stuck fairly well, but I used a roller to press the mats into place on the metal panels, which seemed to help them adhere a little better. Under the old carpet was the type of insulation you'd typically see under carpet in a typical home. It was worn, so I tossed it and installed the new carpet directly over these new mats. The before & after difference in noise was minimal, but noticable. But I only installed them on the floor - not in the doors, rear hatch area, firewall, or roof. So overalll, I'm pleased with these mats as they provided the noise suppression that I had expected.
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Reviewed in the United States on March 20, 2026
★★★★★ 5
Easy to cut and easy to install
Size: 10 sqft, Size: 10 sqft
You receive 9 sheets of RUNSUNSPRII Car Sound Deadening Mat that each measure 9.75" x 15.75". This calculates to a total of 9.6 square feet in total for all of the sheets. Of all the different styles of sound deadening mats, foil lined butyl is the best type for eliminating vibration. This quality product has a printed gridwork of 2-inch squares on the liner to aid in cutting the correct sized pieces.
Even with as sticky as this product is, it is super easy to cut to shape with one pass of a razor blade. OEM auto manufacturers use this same kind of product extensively on the inner structure for sound deadening and to block sound and air transmission through all sizes of holes and cutouts. Because it is highly waterproof, it also is perfect for blocking areas to prevent water intrusion. The very sticky pads adhere to all surfaces and are very flexible and will conform to fit many areas. Because it is thin, it is ideal to install under interior trim panels without causing interference with how the panels fit.
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Reviewed in the United States on January 26, 2026