SKU: 24519929837

PD-L2/B7-DC His Tag Protein, Mouse

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Description

PD-L2/B7-DC His Tag Protein, MouseProduct Specification Species Mouse Synonyms PDL2, PD L2, Butyrophilin B7 DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG2 Accession Q9WUL5 Amino Acid Sequence Leu20 Arg219, with C terminal 8*His LFTVTAPKEVYTVDVGSSVSLECDFDRRECTELEGIRASLQKVENDTSLQSERATLLEEQLPLGKALFHIPSVQVRDSGQYRCLVICGAAWDYKYLTVKVKASYMRIDTRILEVPGTGEVQLTCQARGYPLAEVSWQNVSVPANTSHIRTPEGLYQVTSVLRLKPQPSRNFSCMFWNAHMKELTSAIIDPLSRMEPKVPRGGGSHHHHHHHH Expression System HEK293 Molecular Weight 32 43kDa

Product Specification


Species Mouse
Synonyms PDL2, PD-L2, Butyrophilin B7-DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG2
Accession Q9WUL5
Amino Acid Sequence Leu20-Arg219, with C-terminal 8*His LFTVTAPKEVYTVDVGSSVSLECDFDRRECTELEGIRASLQKVENDTSLQSERATLLEEQLPLGKALFHIPSVQVRDSGQYRCLVICGAAWDYKYLTVKVKASYMRIDTRILEVPGTGEVQLTCQARGYPLAEVSWQNVSVPANTSHIRTPEGLYQVTSVLRLKPQPSRNFSCMFWNAHMKELTSAIIDPLSRMEPKVPRGGGSHHHHHHHH
Expression System HEK293
Molecular Weight 32-43kDa
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Kojima M. et al. (2014) Fusion Protein of Mutant B7-DC and Fc Enhances the Antitumor Immune Effect of GM-CSF-secreting Whole-cell Vaccine. J Immunother. 37(3): 147-154.

Background

B7-DC [also known as programmed death ligand 2 (PD-L2)] is a costimulatory molecule expressed predominantly on dendritic cells (DCs) and macrophages. In addition to its coinhibitory receptor, programmed death receptor 1 (PD-1), evidence suggests that B7-DC interacts with an unidentified costimulatory receptor on T cells. B7-DC mutants with selective binding capacity for the costimulatory receptor may be effective in stimulating antitumor immune responses, while avoiding the inhibitory effects of PD-1.
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SKU: 24519929837

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Connie Strehler
Grantham, US
★★★★★ 5
Comfort and Style
Color: Dark Red, Size: Medium
Very soft, comfortable and versatile. Can dress up or down in this shirt. I love it!
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Reviewed in the United States on May 31, 2026
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Carol
Port Orchard, US
★★★★★ 5
Great buy
Color: White, Size: Large
Great T-shirt if you want something a little dressier than a regular T-shirt. Nice material and fit. Love the little bit longer sleeve.
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Reviewed in the United States on April 26, 2026
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Sandra Giannini
Massapequa, US
★★★★★ 1
Shrunk from M to XS
Color: White, Size: Medium
Shrunk after one wash and very poor quality.
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Reviewed in the United States on May 19, 2026
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Debbie
Bozeman, US
★★★★★ 3
Runs big size chart not accurate
Color: Black, Size: Small
I only put three stars because it runs large. Not a true small. I really wish they had xs. It's too big in neck and shoulders bunch up. The fabric is thick and not at all see through. I like the high neck and half sleeves. The fabric feels soft but also kinda "slick" so some people may not like that feel. For reference I'm barely 5ft and 115 and the small is too big. Not sure if I'm going to keep it or send it back. Price point it is a nice shirt
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Reviewed in the United States on April 25, 2026
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Robin Roberts
Birmingham, US
★★★★★ 5
Comfortable to wear
Color: Black, Size: Large
Comfortable, nice material, looks and feels great. Was thankful that it wasn't overly long. Perfect belly hide but not long
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Reviewed in the United States on April 14, 2026

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