Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 26 - Aug 31
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Mouse Anti-Human CD371 Antibody (S-2850)Product Specification Host Mouse Antigen CD371 Synonyms C type lectin domain family 12 member A; C type lectin like molecule 1 (CLL 1); Dendritic cell associated lectin 2 (DCAL 2); Killer cell C type lectin like receptor L1 (hKLRL1); Myeloid inhibitory C type lectin like receptor (MICL); CLL1; DCAL2; KLRL1; MICL; CLEC12A Location Cell membrane Accession Q5QGZ9 Clone Number S 2850 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu
Product Specification
| Host | Mouse |
| Antigen | CD371 |
| Synonyms | C-type lectin domain family 12 member A; C-type lectin-like molecule 1 (CLL-1); Dendritic cell-associated lectin 2 (DCAL-2); Killer cell C-type lectin-like receptor L1 (hKLRL1); Myeloid inhibitory C-type lectin-like receptor (MICL); CLL1; DCAL2; KLRL1; MICL; CLEC12A |
| Location | Cell membrane |
| Accession | Q5QGZ9 |
| Clone Number | S-2850 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human Peripheral Blood |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 1:200 | Hu |
Background
CD371, also known as CLEC12A, is a type II transmembrane protein with extracellular C-type lectin domains, primarily expressed on myeloid cells. It is a potential myeloid cancer stem cell marker and is considered a target for antibody-based or chimeric antigen receptor T-cell therapies. CD371 is particularly associated with DUX4-rearranged leukemia, where it is highly expressed and serves as a unique cell surface marker. Its expression is also linked to “switch” acute lymphoblastic leukemia (ALL), which has a tendency to switch to monocyte-like cells upon corticosteroid treatment.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy