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Description
Human IgG1 Fc , His tagProduct Specification Species Human Synonyms Immunoglobulin heavy constant gamma 1, Ig gamma 1 chain C region, Ig gamma 1 chain C region EU, Ig gamma 1 chain C region KOL, Ig gamma 1 chain C region NIE, IGHG1 Accession P01857 Amino Acid Sequence Protein sequence(P01857, Asp104 Lys330(D239E,L241E), with C 10*His)
Product Specification
| Species | Human |
| Synonyms | Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1 |
| Accession | P01857 |
| Amino Acid Sequence | Protein sequence(P01857, Asp104-Lys330(D239E,L241E), with C-10*His) DKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEETKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:27.2kDa Actual:30kDa |
| Purity | ＞90% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. Fc binds to various cell receptors and complement proteins. In this way, it mediates different physiological effects of antibodies (detection of opsonized particles; cell lysis; degranulation of mast cells, basophils, and eosinophils; and other processes).
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4.2 ★★★★★
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Product Reviews
★★★★★ 3
Detachable head???
I loved using this nose hair trimmer for a number of months......until I removed
the detachable head. I cannot get the detachable head back onto the groomer...
Any advice???
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Reviewed in the United States on March 3, 2025
★★★★★ 5
Perfect !
Works great! No more batteries. I ordered a green one for my husband.
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Reviewed in the United States on March 9, 2025
★★★★★ 5
Love it
Great! Works well
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Reviewed in the United States on April 5, 2025
★★★★★ 5
Easy to use
Works great!!!!
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Reviewed in the United States on February 3, 2025
★★★★★ 5
Great Everyday Cleanser
One of the best affordable cleansers i’ve ever bought— as someone who’s struggled with hormonal acne for 5 years. Being into skincare for this long, it was hard to find cleansers that were clarifying and effective. Not only have I repurchased this item 4x already, but my family loves it as well. The ingredients are great and the price is amazing for the size. It leaves a good finish on my skin, helping myself feel more clean. The gel consistency is great as someone who’s struggled with both oily and dry skin— it’s been a perfect medium in times of accutane (where my skin was extremely dry) and when oily skin. This doesn’t dry out the skin at all, making it a good option. No significant smell or fragrance— overall the perfect option if you’re looking for a median cleanser.
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Reviewed in the United States on June 27, 2025