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Description
Mouse & Rat & Goat IFN-α1 OneStep ELISA KitProduct Specification Antigen IFN 1 Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Ms, Rt, Gt Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8'C as supplied. Kit Precision Intra assay: 4. 1% Inter assay: 8. 4% Sample type Cell culture supernatant; Serum; Plasma Assay type Sandwich (quantitative) Sensitivity 2. 931 pg mL Range 15. 63 pg mL 1000 pg mL Recovery Cell culture
Product Specification
| Antigen | IFN-α1 |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Reactivity | Ms, Rt, Gt |
| Purification | Protein A |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8'C as supplied. |
Kit
| Precision | Intra-assay: 4.1%； Inter-assay: 8.4% |
| Sample type | Cell culture supernatant; Serum; Plasma |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 2.931 pg/mL |
| Range | 15.63 pg/mL – 1000 pg/mL |
| Recovery | Cell culture supernatant: 105% Serum: 92% Plasma: 84% |
| Assay time | 60 minutes |
| Species reactivity | Ms; Rt; Goat |
Background
Mouse IFN-α1 is a key cytokine belonging to the type I interferon family, which is crucial for the innate immune response against viral infections. It is primarily produced by leukocytes, such as macrophages and dendritic cells, upon detection of viral pathogens. This signaling molecule functions by binding to the ubiquitous interferon-α/β receptor (IFNAR) on the surface of target cells. Upon receptor engagement, it activates the classic JAK-STAT signaling pathway, leading to the expression of numerous interferon-stimulated genes (ISGs). These ISGs establish an antiviral state within cells by inhibiting various stages of viral replication and propagation. Due to its potent immunostimulatory effects, mouse IFN-α1 is extensively used in research to study antiviral mechanisms and immune modulation in murine models. It is also employed as a therapeutic agent in experimental settings to treat viral infections and enhance anti-tumor immunity in mice. Thus, it serves as an essential tool for understanding innate immunity and developing novel immunotherapies.
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