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Description
GPC3/Glypican 3 His Tag Protein, MouseProduct Specification Species Mouse Synonyms GPC3, OCI5, Glypican 3, GTR2 2, MXR7, DGSX, SDYS Accession Q8CFZ4 Amino Acid Sequence Gln25 Met557, with C terminal 10*His
Product Specification
| Species | Mouse |
| Synonyms | GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS |
| Accession | Q8CFZ4 |
| Amino Acid Sequence | Gln25-Met557, with C-terminal 10*His QPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQMMNPGLPESVLDINECLRGARRDLKVFGSFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKILKVAHVEHEETLSSRRRELIQKLKSFINFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSVPKGKVLDKSLDEEGLESGDCGDDEDECIGSSGDGMVKVKNQLRFLAELAYDLDVDDAPGNKQHGNQKDNEITTSHSVGNMGGGSGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 72-130kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Kandil D H. et al. (2009) Glypican-3: a novel diagnostic marker for hepatocellular carcinoma and more. Adv Anat Pathol. 16(2): 125-129. 2、Maeda D. et al. (2009) Glypican-3 expression in clear cell adenocarcinoma of the ovary. Mod Pathol. 22(6): 824-832. |
Background
Glypican-3 (GPC3) belongs to a six-member family of membrane-bound heparan sulfate proteoglycans with a gene that is localized to Xq26.2. GPC3 belongs to a family of Glypicans are heparan sulfate proteoglycans that are bound to the cell surface by glycosyl phosphatidyli nositol. While six members of the glypican family are known in mammals, our study focused on glypican 3(GPC3). Loss-of-function mutations of GPC3 result in the Simpson- Golabi-Behmel syndrome, an X-linked disorder characterized by pre- and postnatal liver and other organ overgrowth. GPC3 is overexpressed in human hepatocellular carcinoma; however, its role in normal liver regeneration and hepatocyte proliferation is unknown. GPC3 is located on the X chromosome, and is highly expressed during embryogenesis and organogenesis. In the adult, on the other hand, GPC3 can only be detected in a limited number of tissues, including the lung, ovaries, mammary epithelium and mesothelium.
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4.3 ★★★★★
Based on 18 reviews
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Product Reviews
★★★★★ 5
Quality suit!
Color: Black, Size: 12, Color: Black, Size: 12
The suit fit my 11 year old son perfectly. He had to dress as Orville Wright for a school biography project. He is lean so it was nice that the pants could be adjusted to fit tighter in the waist.
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Reviewed in the United States on March 10, 2025
★★★★★ 1
Not nice looking
Color: Grey, Size: 14
Looks not nice at all.
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Reviewed in the United States on April 25, 2026
★★★★★ 5
Perfect
Color: Dark Brown, Size: 10
Obtained for one of my grandsons to wear to his big brothers wedding. It fit him perfect and looked so nice perfect color he was so proud to be his brother's best man. The material was breathable so he did not feel to hot. If you are needing a good looking suit you will not go wrong with this company.
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Reviewed in the United States on February 12, 2025
★★★★★ 5
Fantastic!!
Color: Dark Brown, Size: 10
This is the sharp, classy look you want for your child in a child’s suit! It is a nice true fit with a classy look. My son loves this and he was happy with the fit. He is a picky little guy and I was very happy with his response to the fit. The pants had a little glitch but that's ok! I’m so impressed.
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Reviewed in the United States on March 1, 2025
★★★★★ 5
Perfect formal suit!
Color: Black, Size: 16
Great quality and fits perfectly!! I love the vest !!
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Reviewed in the United States on May 14, 2026