Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 29 - Sep 3
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Dopamine D (2) Receptor/D2R Recombinant Rabbit mAb (S-2127-37)Product Specification Host Rabbit Antigen Dopamine D (2) Receptor D2R Synonyms D (2) dopamine receptor; Dopamine D2 receptor; DRD2 Immunogen Synthetic Peptide Location Cell membrane Accession P14416 Clone Number S 2127 37 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu, Ms, Rt Positive Sample Caco 2, SH SY5Y, PANC 1, mouse brain, rat brain Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Antigen | Dopamine D (2) Receptor/D2R |
| Synonyms | D (2) dopamine receptor; Dopamine D2 receptor; DRD2 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P14416 |
| Clone Number | S-2127-37 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | Caco-2, SH-SY5Y, PANC-1, mouse brain, rat brain |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms, Rt |
Background
The dopamine D2 receptor (D2R) is a G protein-coupled receptor encoded by the DRD2 gene, playing a crucial role in the central nervous system. It is the main target for most antipsychotic drugs and is involved in regulating various functions such as motor control, reward, and memory. D2R is coupled to the Gi subtype of G protein, inhibiting adenylyl cyclase activity. In addition to its canonical G protein signaling, D2R also signals through β-arrestin pathways, which can be selectively targeted to potentially improve therapeutic outcomes. Research has shown that D2R is involved in synaptic plasticity and memory formation in mice, and it may protect dopamine neurons from cell death in conditions mimicking Parkinson's disease.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy