SKU: 30837459167

Rat Anti-Mouse CD314 Antibody (S-R664)

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Description

Rat Anti-Mouse CD314 Antibody (S-R664)Product Specification Host Rat Antigen NKG2D Synonyms NKG2 D type II integral membrane protein; Killer cell lectin like receptor subfamily K member 1; NK cell receptor D; NKG2 D activating NK receptor; Nkg2d; Klrk1 Location Cell membrane Accession O54709 Clone Number S R664 Antibody Type Rat mAb Isotype IgG1,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 2 mg ml Conjugation Unconjugated

Product Specification


Host Rat
Antigen NKG2D
Synonyms NKG2-D type II integral membrane protein; Killer cell lectin-like receptor subfamily K member 1; NK cell receptor D; NKG2-D-activating NK receptor; Nkg2d; Klrk1
Location Cell membrane
Accession O54709
Clone Number S-R664
Antibody Type Rat mAb
Isotype IgG1,k
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Ms

Background

NKG2D is a type II transmembrane C-type lectin-like receptor expressed as a disulfide-linked homodimer on virtually all human and mouse NK cells, γδ T cells, and CD8+ αβ T cells; upon engagement by stress-inducible MHC class I–related ligands (MICA/B, ULBPs in humans; Rae-1, H60, Mult1 in mice) it couples to the DAP10 (and in mouse also DAP12) adaptor to deliver phosphotyrosine signals that powerfully lower activation thresholds, costimulate cytotoxicity, and drive proliferation and cytokine release, thereby forming a central surveillance axis that eliminates transformed, infected, or otherwise stressed cells but also contributes to immune-mediated pathologies when ligand expression becomes chronic.

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SKU: 30837459167

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Valarie Amundsen
Phoenix, US
★★★★★ 5
Chews
Size: Extra Small, Color: Blue
Chewy toys to keep my dogs, teeth, healthy very important. This was a very good price and I highly recommend buying it for your puppy.
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Reviewed in the United States on June 11, 2026
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Judy
Alexandria, US
★★★★★ 3
Dog likes some
Size: Extra Small, Color: Blue
Puppy will chew on this but not favorite. Over time it gets sharp pieces and dog could ingest. Not sure how safe for a small dog. Affordable but not long lasting.
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Reviewed in the United States on March 30, 2026
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Teresa mosier
Lake Worth, US
★★★★★ 5
Pug approved
Size: Extra Small, Color: Blue
Bought for my pug to teeth on when he was a puppy. He's almost year old and he still packs his little bone around
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Reviewed in the United States on June 10, 2026
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Amazon Customer
Bozeman, US
★★★★★ 5
Great for teeth cleaning
Size: Extra Small, Color: Blue
My dog loves it. She’s a Yorkie and it’s perfect for her.
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Reviewed in the United States on June 10, 2026
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Tina
Dallas, US
★★★★★ 1
Made for very small dogs- don’t buy if you have medium to large dogs
Size: Extra Small, Color: Blue
2 of my 3 dogs chewed right threw it <5 minutes of getting it causing a potential choking hazard. It’s small not durable but definitely soft. Only suitable for very small dogs
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Reviewed in the United States on April 17, 2026

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