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Description
DMC1 Recombinant Rabbit mAb (S-2166-46)Product Specification Host Rabbit Antigen DMC1 Synonyms Meiotic recombination protein DMC1 LIM15 homolog; DMC1H; LIM15 Immunogen Synthetic Peptide Location Nucleus Accession Q14565 Clone Number S 2166 46 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample HeLa, Raji, K562, Molt 4, F 9, mouse testis, PC 12, rat testis Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical
Product Specification
| Host | Rabbit |
| Antigen | DMC1 |
| Synonyms | Meiotic recombination protein DMC1/LIM15 homolog; DMC1H; LIM15 |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | Q14565 |
| Clone Number | S-2166-46 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | HeLa, Raji, K562, Molt-4, F-9, mouse testis, PC-12, rat testis |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:2000 | Hu, Ms, Rt |
| IHC-P | 1:1000 | Ms, Rt |
Background
DMC1, a meiosis-specific RecA-homologous recombinase conserved from fungi to humans, is indispensable for accurate homologous chromosome segregation during meiosis: it loads onto the single-stranded DNA tails generated at programmed DNA-double-strand breaks, forms octameric rings that encircle the DNA, and drives the search for and strand invasion of homologous chromatids, thereby catalyzing the crossover events that stabilize bivalents; in so doing it works alongside (and partly suppresses) the ubiquitous RAD51, and its absence or mutation causes meiotic arrest, defective synaptonemal-complex formation, and sterility .
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4.6 ★★★★★
Based on 18 reviews
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Product Reviews
★★★★★ 5
Cheap but dependable, easy to clean afterwards
Size: L
Brush works really well on Furs
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 1, 2026
★★★★★ 5
It does the trick.
Size: L
Why did you pick this product vs others?:
Works really well on sheepskins. This tool un -mats and fluffs quite nicely.
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Reviewed in the United States on July 11, 2025
★★★★★ 5
Soft and luxurious, high quality - but don't buy if you have cats
Color: Ivory White, Size: 2' x 6' (Sheepskin Shape)
I give the rug a five-star rating because it deserves it. I was really surprised at how good the rug is right out of the package (it was packaged very well too). Because this rug is relatively less expensive than many other listings of natural sheepskin rugs on Amazon and elsewhere, I wasn't expecting much. But it turned out to be thick, soft, fluffy, plush, and luxurious all over. Many years ago I have purchased another natural sheepskin rug from Amazon described to be of the same size as this one (I got the 2'*6' one), but this one is definitely much bigger in its actual size. It's hands-down a high-quality, high-value purchase if you want a nice natural sheepskin rug. I also love how beautiful the natural creamy white color is.
Now, the story takes a turn. It does have a "natural and organic" smell as mentioned in many other reviews. The smell itself is not repulsive. I don't know how long it will take for it to air out (my last rug never really got rid of the smell, but it was not a big issue since I put it on the floor. I lost the rug in cross country moving.) But now I have a cat! My cat just couldn't resist tackling the rug the moment it was laid on the floor. She probably imagined herself to be a lion or a tiger who just caught some big prey. She couldn't stop kicking and biting the rug, trying to tear it apart. She came back to it a few times after breaks already. And this is day one. I am guessing this smell does stimulate some instinctive call from her genes. In a few short moments, she managed to tear off quite some fur from the edge of the rug... The rug still looks fine since I just received it today. I am not sure how long it will last with my cat though. Before ordering, I thought about this possibility and googled whether cats and sheepskin rugs can co-exist. I got many cute picture results showing angelic cats resting contently in the long and soft sheepskin fur, looking totally adorable and peaceful. Many articles say that natural rugs calm our fluffy friends down. Well, I told myself "perfect!" Win-win for me and my cat. Now, here we are, the beginning of my cat's conquest of an imaginary lamb (which was a real lamb.) I cannot even return it since it has already been damaged by my cat... In the worst case, this rug would become a really expensive cat entertainment piece that would eventually be destroyed....:((( I even started feeling guilty for buying animal-based products - but then comforted myself by remembering reading somewhere that cow and lamb leather goods come from animals that would be slaughtered for meat consumption anyways. My cat is already eating canned food containing Australian lamb, etc, etc. Really need to stop the thoughts.
So this is my review. Beautiful rug of excellent quality and unbeatable value, unless you have a cat(s).
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Reviewed in the United States on April 3, 2022
★★★★★ 5
Good quality, nice looking, cozy
Color: Cream Brown, Size: 2 x 6 ft Sheepskin
Good quality, accurate color. Perfect length for floor beside queen size bed.
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Reviewed in the United States on May 24, 2026
★★★★★ 5
Perfect for a queen bed
Color: Tan, Size: 2' x 6' (Sheepskin Shape), Color: Tan, Size: 2' x 6' (Sheepskin Shape)
I LOVE this rug. I’m so glad I bought this instead of a cheap dupe. Reasonably priced, arrived quickly, doesn’t smell. It’s super soft and fluffy and really dense, so far I haven’t noticed any shedding. The size is perfect for draping across a queen bed. The color is beautiful and feels very natural. I might buy a second one for my bus conversion! Thank you so much!
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Reviewed in the United States on May 5, 2026
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