SKU: 37521936499

PE-Cy7 Mouse Anti-Human CD273 Antibody (S-R590)

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Description

PE-Cy7 Mouse Anti-Human CD273 Antibody (S-R590)Product Specification Host Mouse Antigen CD273 Synonyms Programmed cell death 1 ligand 2; PD 1 ligand 2; PD L2; PDCD1 ligand 2; Programmed death ligand 2; Butyrophilin B7 DC (B7 DC); B7DC; PDCD1L2; PDL2; PDCD1LG2 Location Cell membrane Accession Q9BQ51 Clone Number S R590 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human monocyte derived mature dendritic cells Purification Protein G Concentration 0. 2 mg ml

Product Specification


Host Mouse
Antigen CD273
Synonyms Programmed cell death 1 ligand 2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; Butyrophilin B7-DC (B7-DC); B7DC; PDCD1L2; PDL2; PDCD1LG2
Location Cell membrane
Accession Q9BQ51
Clone Number S-R590
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample Human monocyte-derived mature dendritic cells
Purification Protein G
Concentration 0.2 mg/ml
Conjugation PE-Cy7
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD273, also known as B7-DC or PD-L2, is a 42 kDa type I transmembrane glycoprotein belonging to the B7 family of the immunoglobulin superfamily. It is primarily expressed in dendritic cells, liver, and a few transformed cell lines. CD273 acts as a ligand for the coinhibitory receptor PD-1 (CD279), playing a crucial role in immune regulation by inhibiting T cell activation, proliferation, and cytokine production. Unlike PD-L1, CD273 has a higher affinity for PD-1 and is particularly upregulated in the presence of Th2 cytokines such as IL-4. Additionally, CD273 can also bind to repulsive guidance molecule b (RGMb), which is involved in regulating immune responses through BMP and neogenin signaling pathways.

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Exchange/Return Notes
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SKU: 37521936499

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4.2 ★★★★★
Based on 9 reviews
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Product Reviews
A
Verified Purchase
Amazon Customer
Los Angeles, US
★★★★★ 5
Very good
Color: 4-in-1 Wine Aerator Set - Silver
I'm so glad I bought this wine aerator- it completely exceeded my expectations. It made the wine taste incredibly smooth and high‑quality, almost like an upgraded version of the bottle I opened. The craftsmanship is excellent, and the price is very reasonable for how well it works. Truly a wonderfully made product! :)
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Reviewed in the United States on February 20, 2026
R
Verified Purchase
Ruth Garcia
Whiting, US
★★★★★ 5
The price
Color: 4-in-1 Wine Aerator Set - Silver
For those that like wine. This is the most best think to have . You just press down and let it fill to where you want to. Not afraid to spill .
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 16, 2026
F
Verified Purchase
fotosapien
Port Orchard, US
★★★★★ 3
Doesn't do much to the wine. But a tremendous value if you need one.
Color: 4-in-1 Wine Aerator Set - Silver
Doesn't do much to the wine. But a tremendous value if you need one.
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Reviewed in the United States on May 22, 2026
T
Verified Purchase
TS
Chelsea, US
★★★★★ 5
Great size, design, and 100% metal grinding mechanism
Color: 1pcs-Sliver-304
***PLEASE NOTE: This review is only for the more expensive version here with the all metal grinding mechanism and not the cheaper version that looks the same but has a ceramic grinder that’s also available on this page — hope this helps avoid potential confusion. My advice is to splurge on the metal grinder version. ***UPDATE 3/18/26*** Well, after almost two years of fairly heavy daily use the first flaw has emerged so thought I’d share. Yesterday the silver wrapping on the grinder part came loose making it hard to turn the grinder as it was slipping. I did a quick fix by adding some super glue around the seam at the top of the grinder and that’s done the trick at least for now. I’m leaving my 5-star rating because I remain thrilled with its overall performance and frankly would’ve ordered another one if this fix didn’t work, but so far it appears to be holding. 🤞 So still very happy but just wanted to share in case anyone else experiences this. ***UPDATE 8/18/25*** So I’ve now had this for over a year, and under pretty heavy daily use I’m happy to report it still works as well as the day I bought it. Great product, and it’s a pleasure to use every day. ***UPDATE 10/3/2024*** So, after almost four months of pretty heavy daily use I just wanted to report back that this grinder continues to work perfectly and shows every sign of lasting for years to come. I especially like the glass jar so I can see when I’m running low on black peppercorns, and even though it’s got a small form factor it holds a lot so I don’t have to refill it frequently despite using it multiple times daily. I’m super happy with this product all around and recommend it highly!!! ================================ Been using this for a few days now and am very happy so far. I’ve used a traditional wood pepper mill my whole life, but now it’s just me so I wanted something smaller and with a glass body so I can easily see when I need to add more peppercorns. I also wanted an all metal grinding mechanism (that this version has for an few dollars more) instead of ceramic, which doesn’t seem to hold up as well, and I definitely wanted no plastic parts involved in the actual grinding either — don’t need any more microplastics in my diet thank you. This one seemed to check all the boxes, and so far it’s been great. Initially it was set to a more fine, powdery grind, but it was super easy to adjust to a more course grind that I prefer and it’s perfect. Overall it seems well built and is very easy to use, and as long as this holds up it’s a definite keeper. I’ll report back if any future mishaps, but as of now I’d recommend this very highly!
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Reviewed in the United States on June 21, 2024
S
Verified Purchase
Sandee Childs
Natrona Heights, US
★★★★★ 5
Most excellent spice grinder!
Color: 1pcs-Sliver-304
This spice grinder grinds my cumin and coriander seeds perfectly with very little effort and it’s attractive. I’m sure it will last longer than my plastic one that broke recently. Very happy with my purchase!
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Reviewed in the United States on May 31, 2026

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