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Description
TIE2 His Tag Protein, MouseProduct Specification Species Mouse Synonyms TIE2, Tie 2, TEK, VMCM, VMCM1, CD202b, Angiopoietin 1 receptor Accession Q02858 Amino Acid Sequence Ala23 Leu746, with C 8*His Expression System HEK293 Molecular Weight 92 107kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water
Product Specification
| Species | Mouse |
| Synonyms | TIE2, Tie-2, TEK, VMCM, VMCM1, CD202b, Angiopoietin-1 receptor |
| Accession | Q02858 |
| Amino Acid Sequence | Ala23-Leu746, with C-8*His |
| Expression System | HEK293 |
| Molecular Weight | 92-107kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Jones N. et al. (1998) The Tek / Tie2 receptor signals through a novel Dok-related docking protein, Dok-R. Oncogene. 17(9): 1097-1108. 2、Sato A. et al. (1998) Characterization of TEK receptor tyrosine kinase and its ligands, Angiopoietins, in human hematopoietic progenitor cells. Int Immunol. 10(8): 1217-1227. |
Background
Tie-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis.
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4.8 ★★★★★
Based on 28 reviews
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Product Reviews
★★★★★ 5
This is a great daily user.
Color: Stand Black 1, Size: Battery
The battery life has been wonderful. It is very easy to use. The stand with the frother is very useful. It keeps the counter clean and is easy to grab for use. I use it in many liquid items and it stirs very well. I think the price is good. I would definitely recommend this frother.
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Reviewed in the United States on March 26, 2026
★★★★★ 4
Works well but not good for arthritic hands
Color: Stand Black 1, Size: Battery
Works but it’s hard to handled Have arthritis and not helpful to my hands
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 2, 2026
★★★★★ 5
Happy with my purchase
Color: Stand Black 1, Size: Battery
Really good frother. Works well and I love the stand. My son has been enjoying trying it on all different drinks.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 26, 2026
★★★★★ 5
Great little mixer
Color: Stand Black 1, Size: Battery
Cute little mixer that works well for many drinks.
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Reviewed in the United States on May 29, 2026
★★★★★ 5
Great product
Color: Stand Black 1, Size: Battery
Great product
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Reviewed in the United States on March 13, 2026
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