SKU: 32717739783

GDF-5/BMP-14 Protein, Human

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Description

GDF-5/BMP-14 Protein, HumanProduct Specification Species Human Synonyms BMP14, CDMP1, LAP 4, LPS associated protein 4 Accession P43026 Amino Acid Sequence Ala382 Arg501 Expression System E. coli Molecular Weight 28kDa (Non reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 50mM HAc, pH2. 9 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid

Product Specification


Species Human
Synonyms BMP14, CDMP1, LAP-4, LPS-associated protein 4
Accession P43026
Amino Acid Sequence

Ala382-Arg501

Expression System E.coli
Molecular Weight

28kDa (Non-reducing)

Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer

50mM HAc, pH2.9

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.

Reference

Jin L, Li X. Growth differentiation factor 5 regulation in bone regeneration. Curr Pharm Des. 2013;19(19):3364-73.

Background

Human growth differentiation factor 5 (GDF5) is one of the bone morphogenetic proteins (BMPs) belonging to the transforming growth factor β (TGF-β) superfamily. It has commercial value as a therapeutic protein because of its ability to induce cartilage and bone formation, and angiogenesis in adult animals. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations of GDF5 are associated with several human and animal diseases that are characterized by skeletal deformity such as short digits and short limbs.

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SKU: 32717739783

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4.3 ★★★★★
Based on 28 reviews
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Merry Dillon
Boise, US
★★★★★ 1
fake fake fake
Size: For Large & Medium dogs, Color: beige, Size: For Large & Medium dogs, Color: beige
buyer beware. i don't know what this joke of a "dog toy" is but it's not what is pictured. no chance i'm giving this to my dog since i actually care about his well being. this product says that it's made in china, "patent pending" and that's its "safely tested in USA". also there's a weird stain on the inside of the packaging. no thank you, and i'm about ready to see the blood of whoever is behind potentially putting a dangerous toy in my dogs mouth. HELICOPTER DOG MOM COMING ATCHA
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 3, 2017
A
Verified Purchase
ATC
Massapequa, US
★★★★★ 5
strong chew toy
Size: For Large & Medium dogs, Color: beige
great strong chew toy, keep my dog busy smell strong but dog love it
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 6, 2020
B
Verified Purchase
Ben Bethel
Louisville, US
★★★★★ 5
Perfect for 5 Yorkies - they always go back to these...
Very durable and I'm always hearing my Yorkies gnawing and chewing on these... They really really like them. I've bought antlers and those plastic keys... But these win... The antlers are natural but I've learned they aren't healthy at all, and they still micro-splinter... The keys are too soft and plastic comes off.... These are perfect and I can see the plastic changing shape but not coming off. Perfect win. Oh, and being bright white I can see them in a dim or dark room so I don't step on them, my robot vacuum sees and avoids them, and I can see if my dogs have any bleeding gums, which they haven't had with these yet.
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Reviewed in the United States on January 9, 2023
N
Verified Purchase
Nicole
Massapequa, US
★★★★★ 5
Super chewer loves these!
My super chewer loves these so much they are one of her favorite toys. She chews everything and these last forever
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 8, 2023
R
Verified Purchase
RICHARD W HAASE
Belleville, US
★★★★★ 5
Great chew toy for all size pups
I had to replace a headless / tailless T-Rex. Bargain - I bought a five pack of the large Dinos for less than a three pack of the small ones.
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Reviewed in the United States on January 9, 2024

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