Pay in installments of $74.25 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 27 - Sep 1
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Biotinylated Fc γ RIIIa/CD16a(F176) Avi&His Tag Protein, HumanProduct Specification Species Human Synonyms Fc RIIIa, CD16a, FcR 10 Accession P08637 1 Amino Acid Sequence Gly17 Gln208, with C terminal Avi & 8*His Tag GMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITITQGLAVSTISSFFPPGYQGGGSGLNDIFEAQKIEWHEHHHHHHHH Expression System HEK293 Molecular Weight 45 53kDa Purity >95% by SDS PAGE
Product Specification
| Species | Human |
| Synonyms | Fc γ RIIIa, CD16a, FcR-10 |
| Accession | P08637-1 |
| Amino Acid Sequence | Gly17-Gln208, with C-terminal Avi & 8*His Tag GMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITITQGLAVSTISSFFPPGYQGGGSGLNDIFEAQKIEWHEHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 45-53kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Nimmerjahn F. et al. (2006) Fcgamma receptors: old friends and new family members. Immunity J. 24(1): 19-28. |
Background
Fc gamma RIIIa is a low/intermediate affinity receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, secretion of enzymes and inflammatory mediators, antibody-dependent cytotoxicity and clearance of immune complexes. In humans, it is a 50-70 kDa type I transmembrane activating receptor expressed by NK cells, T cells, monocytes, and macrophages. A single nucleotide polymorphism creates high binding (V176) and low binding (F176) forms that, when homozygous, may influence susceptibility to autoimmune diseases or response to therapeutic IgG antibodies. Aberrant expression or mutations of CD16a is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.5 ★★★★★
Based on 12 reviews
Sort
Product Reviews
★★★★★ 5
Well Made for price and style
Size: 10.5, Color: Black/Ivory
Great fit and very flexible. I also recommend buying shoe savers when purchasing this product. To help with toes wrinkles. The pair itself is stylish and very comfortable. Any purchase of this product will be greatly satisfied.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 16, 2026
★★★★★ 5
Nice shoes
Size: 11.5, Color: Black/Ivory
The are very comfortable, and look great.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 8, 2026
★★★★★ 4
Comfortable
Size: 9.5, Color: British Tan/Ivory
Great foot support. Wore all day with not foot or back pain.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 29, 2026
★★★★★ 5
Quality at affordable prices.
Size: 11.5, Color: British Tan/Ivory
Best old guy shoes. They look great and have support for feet. You don't want cheap department shoes. You will pay for that in your later years.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 11, 2026
★★★★★ 5
Excellent quality, just like the picture
Size: 10.5, Color: White/White
Looks just like the picture.
My bf is a size 10.5 and we got just that and its a perfect fit.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 28, 2026