SKU: 40952765330

TGF-β2 Protein, Human

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Description

TGF-β2 Protein, HumanProduct Specification Species Human Synonyms Transforming growth factor beta 2 proprotein, Cetermin, Glioblastoma derived T cell suppressor factor, G TSF Accession P61812 Amino Acid Sequence Ala303 Ser414 Expression System HEK293 Molecular Weight 12 kDa (Reducing) Purity >95% by SDS PAGE and HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 4mM HCl Reconstitution Reconstitute at 0. 1 1

Product Specification


Species Human
Synonyms Transforming growth factor beta-2 proprotein, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF
Accession P61812
Amino Acid Sequence

Ala303-Ser414
Expression System HEK293
Molecular Weight

12 kDa (Reducing)
Purity >95% by SDS-PAGE and HPLC.
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer

4mM HCl
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in reconstitution buffer after rapid centrifugation.
Stability & Storage

·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
·3 months, -20 to -80℃ under sterile conditions after reconstitution.
·1 week, 2 to 8℃ under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.
Reference

Signal Transduct Target Ther. 2024 Mar 22;9(1):61.
Cytokine Growth Factor Rev. 2006 Feb-Apr;17(1-2):129-39.

Background

TGF-β2 (Transforming Growth Factor-beta 2) is a secreted, 25 kDa disulfide-linked homodimeric cytokine and one of three mammalian TGF-β isoforms. It is synthesized as a 414-aa pre-pro-peptide; after removal of the signal peptide and cleavage of the latency-associated peptide (LAP), the mature 112-aa chain forms the biologically active ligand. TGF-β2 is abundant in bone, cartilage, cornea, kidney, platelets and immune cells, and its expression is rapidly up-regulated after injury or in fibrotic disease. Compared with TGF-β1, TGF-β2 exhibits ~71 % sequence identity but shows distinct promoter regulation and a stronger association with epithelial and neuronal tissues.
TGF-β2 signals through the canonical type II–I receptor serine/threonine kinases TβRII and ALK5, phosphorylating Smad2/3. Phospho-Smad complexes with Smad4 translocate to the nucleus to regulate >500 genes. Non-Smad pathways—PI3K/Akt, mTORC2, MAPK, JAK/STAT3, Rho-GTPases—mediate additional effects on cell survival, migration and EMT.

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Exchange/Return Notes
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SKU: 40952765330

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4.9 ★★★★★
Based on 28 reviews
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Mike M.
West Palm Beach, US
★★★★★ 5
Nice everyday dishes for the price.
Nice everyday dishes for the price. The plates and bowls are generous sizes. The coffee mugs are a bit small if that is a concern. The dishes are sturdy and should hold up well for everyday use.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 28, 2026
D
Verified Purchase
Dan Boone
Fort Morgan, US
★★★★★ 5
Beautiful assortment of 4 place setting!
Beautiful assortment for 4 are remarkably nice to use and look at. The shapes are perfect design.
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Reviewed in the United States on May 17, 2026
J
Verified Purchase
just me
Battle Creek, US
★★★★★ 5
Worth The Money !
Been so many years ago I bought new Dinnerware, not sure how long? But very pleased with this set! and the price!! Packaging was great! No broken pieces.
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Reviewed in the United States on March 4, 2026
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Verified Purchase
John
Los Angeles, US
★★★★★ 5
Great Starter Knife Set With Everything You Need
Size: 9-Piece, Style: Traditional Handle Design
5/5 stars for the Amazon Basics High Carbon Stainless Steel Knife Set. I have been really impressed with this set overall and it has handled pretty much every kitchen task I have thrown at it so far. Right out of the box the knives were insanely sharp and felt much higher quality than I was expecting for the price. One of the biggest pros is the variety of knives included. It comes with basically every knife you would need for normal cooking and kitchen use which makes it a great all-in-one set. The knives also have a really nice weight to them and feel balanced in the hand instead of feeling cheap or flimsy. The grip is nice as well not slippery and while using it I feel like it stays put in my hand. They have held up well with regular use and have been easy to clean after cooking. The high carbon stainless steel has also done a good job resisting rust and staining which is important for a set that gets used often. Another nice addition is the included honing rod which helps maintain the edge and keep the blades performing well over time. I did notice that the edge on the knife I use the most has started to wear down a tiny bit after extended use, but that is expected with pretty much any frequently used kitchen knife and can usually be maintained with regular honing. As for cons, the wooden knife block is nice looking but I could see it potentially cracking over time if it is not taken care of properly or exposed to too much moisture. Other than that, I really do not have many complaints with this set. Overall I think this is a fantastic knife set for anyone who just moved out and needs a complete kitchen setup or for someone wanting to replace an older worn out knife set. I actually gifted a set to my in-laws already and they have been loving it as well. I would definitely recommend it.
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Reviewed in the United States on May 28, 2026
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Verified Purchase
D. E. Reagan
Bozeman, US
★★★★★ 5
Good For Living On The Edge
Size: 9-Piece, Style: Traditional Handle Design
It was past time to replace my dollar store chef knife with a decent set with a bread knife and no steak knives. I first looked at Wüsthof as I always liked that brand, but never owned any. I used a borrowed paring knife for a while and was impressed with the quality. My line cooking time is over and though I would have liked to have a set of forged Wüsthofs, the price was too much for occasional use. My favorite chef knife was a 10" wide Victorinox/Forschner until it got stolen. I replaced it with an 8" version, but it was not wide and felt very different. Still my first choice for stamped high-carbon stainless steel blades. Again, the price for a set was a bit high for use once in a while. I spotted the Amazon Basics 9-Piece Premium Kitchen Knife Block Set. Wait. A forged high carbon stainless steel knife set for that price? I read through all the reviews even the one with the picture of the broken knife, the set seems to be a good buy. Certainly better than a dollar-store knife and a few dollars more than an empty knife block. While I haven't given them a good workout on food yet, I can tell they are very good given the price. I would have liked the chef's knife to be a bit wider, but I can live with it as is. I tried the index finger and thumb holding test on the chef knife and it was comfortable, but not so much on the Santoku knife. I am new to the Santoku Knife. I guess I would hold and use it more like a cleaver. The knives all feel pretty sharp out of the box, though like nearly all new knives, they need some fine-tuning to be really sharp. Sure they are not a top-name branded knife set and if I was still a working line cook I would choose a different set, but as a casual home cook, I like these very much.
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Reviewed in the United States on February 2, 2023

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