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Description
Lck Recombinant Rabbit mAb (SDT-316-15)Product Specification Host Rabbit Antigen Lck Synonyms Tyrosine protein kinase Lck, Leukocyte C terminal Src kinase, LSK, Lymphocyte cell specific protein tyrosine kinase, Protein YT16, Proto oncogene Lck, T cell specific protein tyrosine kinase, p56 LCK Immunogen Recombinant Protein Accession P06239 Clone Number SDT 316 15 Antibody Type Recombinant mAb Application WB, IHC P, ICC, FCM, IP Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5
Product Specification
| Host | Rabbit |
| Antigen | Lck |
| Synonyms | Tyrosine-protein kinase Lck, Leukocyte C-terminal Src kinase, LSK, Lymphocyte cell-specific protein-tyrosine kinase, Protein YT16, Proto-oncogene Lck, T cell-specific protein-tyrosine kinase, p56-LCK |
| Immunogen | Recombinant Protein |
| Accession | P06239 |
| Clone Number | SDT-316-15 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC, FCM, IP |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| ICC | 1:500 | |
| IP | 1:50 | |
| IHC-P | 1:2000 | |
| FCM | 1:500 |
Background
Lck (or lymphocyte-specific protein tyrosine kinase) is a 56 kDa protein that is found inside specialized cells of the immune system called lymphocytes. The Lck is a member of Src kinase family (SFK), it is important for the activation of the T-cell receptor signaling in both naive T cells and effector T cells. The role of the Lck is less prominent in the activation or in the maintenance of memory CD8 T cells in comparison to CD4 T cells. In addition, the role of the lck varies among the memory T cells subsets [PMID: 27271569].
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