Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 24 - Aug 29
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
PSAT1 Recombinant Rabbit mAb (S-3054-5)Product Specification Host Rabbit Antigen PSAT1 Synonyms Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase (PSAT); PSA Immunogen Recombinant Protein Location Cytoplasm Accession Q9Y617 Clone Number S 3054 5 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu Positive Sample HEK 293, HepG2, HeLa, K562 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid
Product Specification
| Host | Rabbit |
| Antigen | PSAT1 |
| Synonyms | Phosphoserine aminotransferase; Phosphohydroxythreonine aminotransferase (PSAT); PSA |
| Immunogen | Recombinant Protein |
| Location | Cytoplasm |
| Accession | Q9Y617 |
| Clone Number | S-3054-5 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC |
| Reactivity | Hu |
| Positive Sample | HEK-293, HepG2, HeLa, K562 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| ICC | 1:100 | Hu |
Background
PSAT1 (phosphoserine aminotransferase 1) is a pyridoxal-5′-phosphate-dependent enzyme that catalyzes the reversible conversion of 3-phosphohydroxypyruvate and glutamate into 3-phosphoserine and α-ketoglutarate, representing the second step in the de novo L-serine biosynthesis pathway that fuels one-carbon metabolism, nucleotide and phospholipid production, and cellular redox balance; highly expressed in liver, brain and proliferating tissues, PSAT1 is frequently up-regulated in multiple cancers where its increased activity supports tumor growth, metastasis and chemoresistance by maintaining serine/glycine homeostasis and NADPH generation through mitochondrial and cytosolic isoforms, while inherited mutations in PSAT1 cause Neu-Laxova syndrome, a severe congenital disorder characterized by microcephaly, ichthyosis and lethality, underscoring its essential role in both normal development and disease.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy