SKU: 46604822283

SEZ6 Recombinant Rabbit mAb,PBS Only(SDT-2097-737)

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Description

SEZ6 Recombinant Rabbit mAb,PBS Only(SDT-2097-737)Product Specification Host Rabbit Antigen SEZ6 Synonyms Seizure protein 6 homolog; SEZ 6; hSEZ 6 Immunogen Recombinant Protein Location Cell membrane Accession Q53EL9 Clone Number SDT 2097 737 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample H69 Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of

Product Specification


Host Rabbit
Antigen SEZ6
Synonyms Seizure protein 6 homolog; SEZ-6; hSEZ-6
Immunogen Recombinant Protein
Location Cell membrane
Accession Q53EL9
Clone Number SDT-2097-737
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P
Reactivity Hu
Positive Sample H69
Purification Protein A
Concentration 1 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000-1:10000 Hu
IHC-P 1:2000 Hu

Background

SEZ6 (Seizure-related gene 6) is a type I transmembrane glycoprotein (~110 kDa) composed of five short consensus repeat (SCR) domains, three CUB domains, a single transmembrane segment and a short cytoplasmic tail that is predominantly expressed in the central nervous system, where it acts as a critical trafficking chaperone for kainate receptor subunits GluK2/3, ensuring their proper N-glycosylation (including the HNK-1 epitope), post-ER export and surface localization to regulate synaptic connectivity, long-term potentiation and dendritic arbor balance, and is sequentially cleaved by BACE1 and γ-secretase to release a soluble ectodomain whose CSF level serves as a direct pharmacodynamic read-out of BACE1 inhibition, while in neuroendocrine neoplasms its selective over-expression is exploited as an ADC target for therapies against small-cell lung cancer and related tumors.

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SKU: 46604822283

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Natasha Spencer
Massapequa, US
★★★★★ 3
Cheap
Size: 6FT*6FT, Color: Black
They serve their purpose as long as you leve them in one place and not moving them around and they're kinda flimsy and some of the velcros are cut too short and can't stay closed
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Reviewed in the United States on April 18, 2026
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Jennifer D
Waukegan, US
★★★★★ 5
Really adorable & functional room divider! I love mine!
Color: Dark Coffee, Size: 4 Panel
Really beautiful divider. I use it out on my patio at my apartment building to provide privacy, shade & keep my things safe. At 6 foot tall and 4 panels (I strongly suggest 4 panels) it's quite a lovely addition to my home. It's delicate so handle carefully but it comes completely put together & just set it up. Being able to move it inside or outside or wherever because it's so light makes it very mobile. It's not too opaque you can see through it but if it's for total privacy use a tablecloth or something behind it to make it less see through. It's strong and big and I had a question for their cs and they responded immediately and handled it right away which is a sign of a good company. It's light so make sure you secure it if it's windy for stability.
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Reviewed in the United States on April 14, 2026
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Amazon Customer
New York, US
★★★★★ 5
Nice Look
Color: Dark Coffee, Size: 8 Panel
Attractive and Very versatile. Pretty sturdy, but use care if you buy larger screens when moving. Hinges are small so moving it recklessly could break them. Overall I would recommend this screen. I love it
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Reviewed in the United States on May 20, 2026
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Agnes
Boise, US
★★★★★ 5
Beautiful folding screen😊
Color: Light Beige, Size: 3 Panel
Well made and perfect height I needed
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Reviewed in the United States on May 25, 2026
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Nuke
Lexington, US
★★★★★ 4
I Like it...Perfect sunscreen to keep the Sun off me: I Need To Test Outside Durability
Color: Natural, Size: 4 Panel, Color: Natural, Size: 4 Panel
I have Southern exposure on my 6th story balcony. For most of the year, the Sun out there is unbearable. I have had another room divider/sunscreen I have outside in all weather conditions for 9 years...and it has held up well and still going (but showing age). Hoping this one will be as durable. I will update my review after some weather conditions have put it through its paces. The divider is quite attractive and lightweight. It is perfect for what I need it for at this time, and is stable in the wind with the anchoring system I have used.
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Reviewed in the United States on August 30, 2024

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