SKU: 49194365118

MAGE-A4 Recombinant Rabbit mAb (S-3868-66)

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Description

MAGE-A4 Recombinant Rabbit mAb (S-3868-66)Product Specification Host Rabbit Antigen MAGE A4 Synonyms Melanoma associated antigen 4; Cancer testis antigen 1. 4 (CT1. 4); MAGE 4 antigen; MAGE 41 antigen; MAGE X2 antigen; MAGE4; MAGEA4 Immunogen Synthetic Peptide Location Nucleus Accession P43358 Clone Number S 3868 66 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid

Product Specification


Host Rabbit
Antigen MAGE-A4
Synonyms Melanoma-associated antigen 4; Cancer/testis antigen 1.4 (CT1.4); MAGE-4 antigen; MAGE-41 antigen; MAGE-X2 antigen; MAGE4; MAGEA4
Immunogen Synthetic Peptide
Location Nucleus
Accession P43358
Clone Number S-3868-66
Antibody Type Recombinant mAb
Isotype IgG
Application IHC-P
Reactivity Hu
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
IHC-P 1:2000 Hu

Background

MAGE-A4 (Melanoma-Associated Antigen A4) is a cancer-testis antigen belonging to the MAGE-A family, which is normally expressed exclusively in immune-privileged sites such as the testis and placenta but is aberrantly reactivated in a wide variety of malignant tumors including synovial sarcoma, lung squamous cell carcinoma, head and neck cancers, and melanoma. As an intracellular protein processed and presented on the cell surface by Major Histocompatibility Complex (MHC) class I molecules, MAGE-A4 serves as a highly specific tumor-associated antigen that is largely absent from normal somatic tissues, making it an attractive target for immunotherapeutic strategies such as T-cell receptor (TCR)-engineered T cells, peptide vaccines, and antibody-drug conjugates. Its expression is often correlated with tumor progression and poor prognosis in certain cancers, and because of its restricted normal tissue distribution, therapies targeting MAGE-A4 aim to maximize tumor killing while minimizing off-target toxicity, although careful monitoring is required due to potential low-level expression in some normal tissues or the risk of cross-reactivity with other MAGE family members.

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SKU: 49194365118

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Geoff Cole
Louisville, US
★★★★★ 5
Easy to store and use salt and pepper
Color: Upgrade Silver, Size: Rechargeable
Love these - super easy to use!!!!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 9, 2026
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Charmed
Houston, US
★★★★★ 5
Worth the buy!
Color: Upgrade Silver, Size: Rechargeable
Great product!
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Reviewed in the United States on May 13, 2026
B
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Believer247
Boise, US
★★★★★ 3
Mediocre salt and pepper grinders
Color: Upgrade Silver, Size: Rechargeable
Pros: They do work, and they are rechargeable. Cons: the motors run really slow, capacity is low, The charging tray you have to empty frequentlyto reduce buildup underneath the salt and pepper grinders.
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Reviewed in the United States on March 3, 2026
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Bibi
Lake Worth, US
★★★★★ 5
Sleek and classy
Color: Upgrade Silver, Size: Rechargeable
I love that these are rechargeable
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Reviewed in the United States on April 25, 2026
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Walnut Creek Lady
Battle Creek, US
★★★★★ 5
Excellent Pepper Grinder
Color: Upgrade Black, Size: Rechargeable
I've had several pepper grinders over the years, and none was as easy and smooth to use as this one. It fills easily, and it grinds evenly and smoothly with a gentle press of the button. I am glad there are two, just in case one does give out, I will have the other to use, as I am not interested in grinding salt. It runs so effortlessly that you have to be a little careful when picking it up that you do not accidentally engage the button before you want the pepper to come out. I love it, and came back here after using it for two months just to let you know.
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Reviewed in the United States on April 26, 2026

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