SKU: 49879095742

S-RMab® CD68 Recombinant Mouse mAb (SDT-R146)

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Description

S-RMab® CD68 Recombinant Mouse mAb (SDT-R146)Product Specification Host Mouse Antigen CD68 Synonyms KP1, PGM1, Macrosialin, Gp110 Immunogen N A Location Membrane, Lysosome, Endosome Accession P34810 Clone Number SDT R146 Antibody Type Recombinant mAb Isotype IgG1 Application IHC P, ICC Reactivity Hu Purification Protein G Concentration 0. 4 mg ml Tag N A Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt

Product Specification


Host Mouse
Antigen CD68
Synonyms KP1, PGM1, Macrosialin, Gp110
Immunogen N/A
Location Membrane, Lysosome, Endosome
Accession P34810
Clone Number SDT-R146
Antibody Type Recombinant mAb
Isotype IgG1
Application IHC-P, ICC
Reactivity Hu
Purification Protein G
Concentration 0.4 mg/ml
Tag N/A
Physical Appearance Liquid
Storage Buffer PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
IHC-P 1:1000 null
ICC 1:25 null

Background

CD68 (Cluster of Differentiation 68) is a protein highly expressed by cells in the monocyte lineage (e.g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages. Immunohistochemistry can be used to identify the presence of CD68, which is found in the cytoplasmic granules of a range of different blood cells and myocytes. It is particularly useful as a marker for the various cells of the macrophage lineage, including monocytes, histiocytes, giant cells, Kupffer cells, and osteoclasts. This allows it to be used to distinguish diseases of otherwise similar appearance, such as the monocyte/macrophage and lymphoid forms of leukaemia (the latter being CD68 negative). Its presence in macrophages also makes it useful in diagnosing conditions related to proliferation or abnormality of these cells, such as malignant histiocytosis, histiocytic lymphoma, and Gaucher's disease.

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Exchange/Return Notes
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SKU: 49879095742

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