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Description
SR-B2/LIMPII Fc Chimera Protein, HumanProduct Specification Species Human Synonyms SR B2, SCARB2, CD36L2, LIMP2, LIMPII Accession Q14108 Amino Acid Sequence Arg27 Thr432, with C terminal human IgG1 Fc
Product Specification
| Species | Human |
| Synonyms | SR-B2, SCARB2, CD36L2, LIMP2, LIMPII |
| Accession | Q14108 |
| Amino Acid Sequence | Arg27-Thr432, with C-terminal human IgG1 Fc RVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTIEGRMDPKSSDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Expression System | HEK293 |
| Molecular Weight | 87-107kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Neculai D. et al. (2013) Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36. Nature. 504: 172-176. |
Background
LIMPII (Lysosomal Integral Membrane Protein II), also known as LPG85 (85 kDa lysosomal membrane sialoglycoprotein) and as CD36 antigen-like 2 (CD36L2), is a major lysosomal membrane protein. LIMP-II is a type-III protein that traverses the membrane twice, with an N-terminal transmembrane anchor as a result of an uncleaved signal peptide and a second membrane spanning region near the C-terminus, followed by a 20 amino acid cytoplasmic tail. LIMPII is currently known to be a member of a superfamily of scavenger receptor proteins (class B), which also includes scavenger receptor (SR)-B1 and SR-B3. These three proteins share their structure, which comprises two transmembrane domains, a relatively large extracellular domain, and both the amino and carboxyl termini located within the cytoplasm. LIMPII as the mannose-6-phosphate- independent trafficking receptor for beta-glucocerebrosidase.
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4.1 ★★★★★
Based on 20 reviews
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Product Reviews
★★★★★ 5
Wonderful tips for young adults beginning their journey into adulthood!
Format: Kindle
If only we were all taught these basic skills before we leave home. Unfortunately, that is not always the case. This is where a book like Life Skills comes in as an excellent teacher of learning those necessary skills! Great book, easy to understand, full of great advice.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 6, 2022
★★★★★ 5
Good tips for teens and not so young
Format: Kindle
This booklet is a good read for teens to get the most important facts about how to manage their finances. It offers great tips for everybody, too.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 6, 2023
★★★★★ 3
Too simple
Format: Kindle
Some of the information is inaccurate or out of date such as the food pyramid. Much of should have been learned long before they are ready to leave home. But some of it such as the simple recipes and the cleaning solutions are useful. I wish the author had spent a little time to address teens with disabilities and other special circumstances. All in all a decent book but the author could have done so much more.
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Reviewed in the United States on June 2, 2022
★★★★★ 5
Very Informative About Little Known ,But Important History
Format: Hardcover
My Dad likes the history which he has learned from Jim Clyburn. He learned more details about the Eight.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 23, 2026
★★★★★ 5
Clyburn captures the past to warn us about the present and future.
Format: Hardcover
I enjoy this book. The history of white Conservatives first taking the black vote away by domestic terrorism and violence and then changing the rules to make getting the vote back nearly impossible explains the 70 year gap between the first eight and the ninth (Clyburn). He mixes the past record of lying and dirty tricks of Conservatives with current events that attempt to bring about the same result. Thanks for all of your work in bringing this great history. It should admonish all of us to work to make sure we don't fall victim to the lying and dirty tricks of the Conservatives of the present.
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Reviewed in the United States on May 14, 2026
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