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Description
α-synuclein His tag Protein, HumanProduct Specification Species Human Synonyms alpha synuclein; Non A beta component of AD amyloid; Non A4 component of amyloid precursor (NACP); SNCA; NACP; PARK1; Accession P37840 Amino Acid Sequence Met1 Ala140, with C 10*His Expression System E. coli Molecular Weight Theoretical: 16. 1kDa Actual: 20kDa Purity >95% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4.
Product Specification
| Species | Human |
| Synonyms | alpha-synuclein;Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor (NACP); SNCA; NACP; PARK1; |
| Accession | P37840 |
| Amino Acid Sequence |
Met1-Ala140, with C-10*His
|
| Expression System | E.coli |
| Molecular Weight |
Theoretical: 16.1kDa Actual: 20kDa
|
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer |
PBS, pH7.4.
|
| Reconstitution |
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
|
| Stability & Storage |
|
Background
Alpha-synuclein is a neuronal protein that regulates synaptic vesicle trafficking and subsequent neurotransmitter release. It is abundant in the brain, while smaller amounts are found in the heart, muscle and other tissues. In the brain, alpha-synuclein is found mainly in the axon terminals of presynaptic neurons. Within these terminals, alpha-synuclein interacts with phospholipids and proteins. It plays a role in restricting the mobility of synaptic vesicles, consequently attenuating synaptic vesicle recycling and neurotransmitter release.
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