Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 30 - Sep 4
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Phospho-STING (Ser366) Recombinant Rabbit mAb (S-2243-62)Product Specification Host Rabbit Antigen Phospho STING (Ser366) Synonyms Stimulator of interferon genes protein; hSTING; Endoplasmic reticulum interferon stimulator (ERIS); Mediator of IRF3 activation (hMITA); Transmembrane protein 173; ERIS; MITA s; STING s; TMEM173; STING1 Immunogen Synthetic Peptide Location Cytoplasm, Lysosome, Mitochondrion, Cell membrane, Endoplasmic reticulum Accession Q86WV6 Clone Number S 2243 62 Antibody Type Recombinant
Product Specification
| Host | Rabbit |
| Antigen | Phospho-STING (Ser366) |
| Synonyms | Stimulator of interferon genes protein; hSTING; Endoplasmic reticulum interferon stimulator (ERIS); Mediator of IRF3 activation (hMITA); Transmembrane protein 173; ERIS; MITA s; STING s; TMEM173; STING1 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Lysosome, Mitochondrion, Cell membrane, Endoplasmic reticulum |
| Accession | Q86WV6 |
| Clone Number | S-2243-62 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| Dot Blot | 1:1000 | |
| WB | 1:1000-1:2000 | Hu |
Background
Phospho-STING (Ser366) protein is a phosphorylated form of the stimulator of interferon genes (STING) protein, specifically phosphorylated at serine 366. STING is a key component of the innate immune system, playing a crucial role in the cytosolic DNA sensing pathway. When phosphorylated at Ser366, STING is activated and promotes the production of type I interferons and other pro-inflammatory cytokines in response to pathogen-associated molecular patterns or DNA damage. This phosphorylation event is essential for the downstream signaling cascade that leads to the activation of immune cells and the initiation of an antiviral or antibacterial response. Abnormal regulation of Phospho-STING (Ser366) has been implicated in various immune-related diseases, making it a potential target for therapeutic interventions.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy