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Description
S-RMab® S100B Recombinant Rabbit mAb,PBS Only (SDT-518-45)Product Specification Host Rabbit Antigen S100B Synonyms Protein S100 B, S 100 protein beta chain Immunogen Synthetic Peptide Location Cytoplasm, Nucleus, Secreted Accession P04271 Clone Number SDT 518 45 Antibody Type Recombinant mAb Application WB, IHC P, IP Reactivity Hu, Ms, Rt Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt
Product Specification
| Host | Rabbit |
| Antigen | S100B |
| Synonyms | Protein S100-B, S-100 protein beta chain |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus, Secreted |
| Accession | P04271 |
| Clone Number | SDT-518-45 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, IP |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC | 1:1000-1:2000 | |
| IP | 1:50 |
Background
S100B is a Ca2+-binding protein, which is secreted from astrocytes. S100B is widely expressed in astrocytes, certain neuronal populations, Schwann cells, myeloid-derived cells, and a few other cell types. In diagnostic pathology, S100B – also termed “S100” – is used as a marker for Schwann cells and melanocytes. In these cell types, S100B is highly expressed, however, S100B is also regularly seen in various other cell types. It is mainly used for differentiated diagnosis of malignant melanoma, cartilagea, and neurological tumors.
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