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Description
p38 MAPK Recombinant Rabbit mAb (S-508-19)Product Specification Host Rabbit Antigen p38 MAPK Synonyms Mitogen activated protein kinase 14, MAP kinase 14, MAPK14, CSAID binding protein, CSBP, MAP kinase MXI2, MAX interacting protein 2, MAP kinase p38 alpha, SAPK2a Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession Q16539 Clone Number S 508 19 Antibody Type Recombinant mAb Application WB, IHC P, ICC, ICFCM Reactivity Hu, Ms, Rt Predicted Reactivity Zf, Fs, Cz, Dg Purification
Product Specification
| Host | Rabbit |
| Antigen | p38 MAPK |
| Synonyms | Mitogen-activated protein kinase 14, MAP kinase 14, MAPK14, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, MAP kinase p38 alpha, SAPK2a |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | Q16539 |
| Clone Number | S-508-19 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC, ICFCM |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Zf, Fs, Cz, Dg |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:5000 | |
| IHC | 1:1000 | |
| ICC | 1:500 | |
| ICFCM | 1:500 |
Background
p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines, ultraviolet irradiation, heat shock, and osmotic shock, and are involved in cell differentiation, apoptosis and autophagy. Abnormal activity (higher or lower than physiological) of p38 has been implicated in pathological stresses in several tissues, that include neuronal, bone, lung, cardiac and skeletal muscle, red blood cells, and fetal tissues.
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