SKU: 68859034748

Human ART1 Protein, His tag

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Description

Human ART1 Protein, His tagProduct Specification Species Human Synonyms GPI linked NAD(P)(+) arginine ADP ribosyltransferase 1, ADP ribosyltransferase C2 and C3 toxin like 1 (ARTC1), Mono(ADP ribosyl)transferase 1, CD296 Accession P52961 Amino Acid Sequence Protein sequence (P52961, Gln23 Asn294, with C His tag)

Product Specification


Species Human
Synonyms GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1, ADP-ribosyltransferase C2 and C3 toxin-like 1 (ARTC1), Mono(ADP-ribosyl)transferase 1, CD296
Accession P52961
Amino Acid Sequence

Protein sequence (P52961, Gln23-Asn294, with C-His tag) QSHPITRRDLFSQEIQLDMALASFDDQYAGCAAAMTAALPDLNHTEFQANQVYADSWTLASSQWQERQARWPEWSLSPTRPSPPPLGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGQRPPRCHQVFRGVHGLRFRPAGPRATVRLGGFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRLAQGPARIYLRALGKHSTYNCEYIKDKKCKSGPCHLDN

Expression System HEK293
Molecular Weight

Predicted MW: 32.1 kDa Observed MW: 38 kDa

Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag with C-His tag
Physical Appearance Lyophilized Powder
Storage Buffer

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

ART1 is a cell - surface protein. It belongs to the ADP - ribosyltransferase family and plays diverse roles in multiple cellular activities. In the immune system, CD296 is involved in T - cell activation and immune regulation, thereby influencing the intensity and direction of immune responses. For example, it may modulate the signaling pathways that determine whether T - cells proliferate, differentiate, or become activated to combat pathogens. In cancer research, abnormal expression of CD296 has been detected in some tumor cells. This aberrant expression is potentially linked to critical tumor - related processes such as cell proliferation, migration, and immune escape.

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SKU: 68859034748

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