SKU: 68919365092

FOXM1 Recombinant Rabbit mAb (S-2529-26)

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Description

FOXM1 Recombinant Rabbit mAb (S-2529-26)Product Specification Host Rabbit Antigen FOXM1 Synonyms Forkhead box protein M1; Forkhead related protein FKHL16; Hepatocyte nuclear factor 3 forkhead homolog 11 (HFH 11; HNF 3 fork head homolog 11); M phase phosphoprotein 2; MPM 2 reactive phosphoprotein 2; Transcription factor Trident; Winged helix factor from INS 1 cells; FKHL16; HFH11; MPP2; WIN Immunogen Synthetic Peptide Location Nucleus Accession Q08050 Clone Number S 2529 26 Antibody Type

Product Specification


Host Rabbit
Antigen FOXM1
Synonyms Forkhead box protein M1; Forkhead-related protein FKHL16; Hepatocyte nuclear factor 3 forkhead homolog 11 (HFH-11; HNF-3/fork-head homolog 11); M-phase phosphoprotein 2; MPM-2 reactive phosphoprotein 2; Transcription factor Trident; Winged-helix factor from INS-1 cells; FKHL16; HFH11; MPP2; WIN
Immunogen Synthetic Peptide
Location Nucleus
Accession Q08050
Clone Number S-2529-26
Antibody Type Recombinant mAb
Isotype IgG
Application WB, IHC-P
Reactivity Hu
Positive Sample HT-29, A431, HeLa
Purification Protein A
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu
IHC-P 1:200 Hu, Ms, Rt

Background

FOXM1 is a transcription factor of the Forkhead box family that orchestrates cell-cycle progression by directly activating genes required for G1/S and G2/M transitions, DNA replication, and mitosis; its expression is normally low in quiescent cells but rises sharply from late G1 through M phase, and it is frequently over-expressed in human cancers where it promotes proliferation, angiogenesis, metastasis, and chemo-radiotherapy resistance through pathways including PI3K/AKT, Wnt/β-catenin, and p53; post-translational modifications such as phosphorylation by CDK, PLK1 and AKT, together with ubiquitin-mediated degradation, tightly regulate FOXM1 activity, making it both a key biomarker for poor prognosis and an attractive therapeutic target in oncology.

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Exchange/Return Notes
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SKU: 68919365092

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4.0 ★★★★★
Based on 9 reviews
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C
Verified Purchase
CSI AJ
West Palm Beach, US
★★★★★ 4
Warm, comfortable booties
Size: 12-13, Color: Red/Black Check
I would give these booties a 5 star because they are soft, warm, comfortable, high on my ankle and a color I appreciate. They are easy to slip on NOW. I say "NOW" because I have a deformed foot due to being broken. That foot was hard to get the bootie on. After 1 try in which some of the stitching came out; it's easy to put on. The stitching came out far to easily. There are 3 lines of stitching. One line between the sole and 1st layer of polar fleece. That line has had no problem. The other 2 lines have each come out abt 3 inches. I got size 12
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 17, 2026
R
Verified Purchase
R Secrest
Whiting, US
★★★★★ 5
Very Warm and Comfortable
Size: 12-13, Color: Red/Black Check
Love these. Just like walking on a cloud. They are very warm. Note there is no L or R, fits either foot.
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Reviewed in the United States on April 30, 2026
G
Verified Purchase
Geobub
Pawtucket, US
★★★★★ 3
Seams Separate Quickly
Size: 8-9, Color: Red/Black Check
They fall apart. The seams are terrible and almost immediately separate. Although they are warm and comfortable until stuff comes through the separated seams.
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Reviewed in the United States on March 29, 2026
D
Verified Purchase
David Pritchett
Los Angeles, US
★★★★★ 5
Meeting my expectations....
Size: 14-15, Color: Grey/White Check
I am a male with pretty large feet (Mens size 14US) and wanted some very warm slippers to wear around the house. I have nerve issues in my toes and if I don't keep my feet very warm they start to hurt. I wanted something both comfortable and warm. I received these a few days ago and so far they have done a great job at keeping my feet warm. The linings are thick and fluffy and the bottoms feel like they have a memory foam inner sole in them. The tops can either be worn up or rolled down. The actual soles are a soft leather-like material. They are thicker than normal cloth, but not hard like rubber soled slippers (I actually wanted something that was more of a slipper and less of a "shoe"). The only down side is that they don't really seem to have a left and right to them (both slippers seem identical), and for awhile no matter how I wore them, they felt a bit like they were on the wrong feet. However, they seem to have formed themselves to my feet and now (through wearing them) it definitely feels like there is a left and a right. I don't know how long these will last, but they were not expensive, so if I get a few months of wear from them, I will be happy and will just order another pair when these wear out. They aren't the most attractive slippers in the world, but they aren't horrible looking and they are very functional.
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Reviewed in the United States on February 24, 2025
J
Verified Purchase
John Palmer
Whiting, US
★★★★★ 4
for polar fleece slippers with leather soles, these are quite nice
Size: 8-9, Color: Red/Black Check
I bought these to replace some Mug Lugs slippers last fall after they had started to come apart from barely a year of use (they were knitted) and have been wearing them constantly since then. The polar fleece does easily pill somewhat but get a hard use and are quite comfortable too. I wear these in the house most of the time as my feet do not like to wear shoes all day. They are comfortable, and do seem to hold up well. The only other issue is until I get my office chair mat replaced, these catch and can cause problems and have a little, but not enough to worry too much about. They supposedly have an anti slip design on the bottom, but if flour falls on the kitchen floor, not so slip resistant. I chose these as one, they are red, but also plaid and like them a lot. Hopefully, I get more than a years use out of them. I have had several polar fleece sock type slippers similar to these in the past, and the last polar fleece pair in Dk Blue and from Land End finally after several years of constant use, the stitching began to come apart and the sole was separating from the body of the slipper on one slipper. They do keep the feet warm, with or without socks and can, at times, get my feet too warm but I enjoy them quite a bit.
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Reviewed in the United States on May 3, 2025

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