Pay in installments of $43.75 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 9 - Sep 14
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 700 Mouse Anti-Human CD158 Antibody (S-2918)Product Specification Host Mouse Antigen CD158 Synonyms CD158a; CD158g; CD158h; KIR2DL1; KIR2DS1; KIR2DS3; KIR2DS5 Location Cell membrane Accession P43626Q14953Q14954 Clone Number S 2918 Antibody Type Mouse mAb Isotype IgG2b,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein A Concentration 0. 2 mg ml Conjugation Alexa Fluor 700 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12
Product Specification
| Host | Mouse |
| Antigen | CD158 |
| Synonyms | CD158a; CD158g; CD158h; KIR2DL1; KIR2DS1; KIR2DS3; KIR2DS5 |
| Location | Cell membrane |
| Accession | P43626、Q14953、Q14954 |
| Clone Number | S-2918 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Purification | Protein A |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 700 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Hu |
Background
CD158, also known as killer-cell immunoglobulin-like receptor (KIR), is a polymorphic type I transmembrane glycoprotein expressed chiefly on natural killer (NK) cells and subsets of T cells that recognizes specific HLA class I allotypes (HLA-A, -B or -C) and transmits either inhibitory or activating signals—depending on whether its cytoplasmic tail contains ITIMs or associates with the ITAM-bearing adaptor DAP12—to regulate cytotoxic activity, thereby serving as a critical immune checkpoint whose blockade is being explored clinically to unleash NK-cell mediated anti-tumor responses.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.0 ★★★★★
Based on 14 reviews
Sort
Product Reviews
★★★★★ 5
Long lasting dog treat
Flavor Name: Bacon, Size: 1 Count (Pack of 1)
My dog absolutely loved this stuffed shin bone—it kept her occupied way longer than most treats, which is always a win. It’s a great option when you need something that will actually hold their attention.
What I Loved:
• Long-lasting chew compared to typical treats
• The stuffing inside keeps dogs interested and engaged
• Helps with boredom and keeps them busy
• Once finished, the bone can be reused with other fillings
One Small Con:
• It can get a little messy depending on how your dog chews, so it’s best to give it in an easy-to-clean area
Who It’s Best For:
Perfect for medium to strong chewers or dogs that need something to keep them occupied for a while.
Final Verdict:
This is a great value and a go-to for keeping dogs entertained. I’d definitely recommend it if you’re looking for a longer-lasting treat that your dog will actually stick with! 🐾
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 11, 2026
★★★★★ 5
🦴 The Ultimate Distraction: A Must-Have for Power Chewers!
Flavor Name: Bacon, Size: 1 Count (Pack of 1)
Finding a chew toy that can withstand my 70-pound "House Hippo" (an expert-level destructor) for more than ten minutes felt impossible, until we discovered these stuffed shin bones. These treats are an absolute game-changer for long-lasting entertainment, durability, and distraction.
Exceptional Durability and Value:
The bone itself is thick, natural, and surprisingly sturdy. Unlike processed chews that crumble or get demolished instantly, these last for days of chewing. The value is tremendous because they provide two phases of entertainment: first, the intense effort of licking out the filling, and second, the satisfying work of chewing the bone itself afterward.
Irresistible Appeal (Peanut Butter/Cheese Filling):
The filling is the secret weapon! My dog goes absolutely wild for the flavor. The filling is firmly packed inside, which means he has to spend a significant amount of time actively working to get every last bit. This intense focus buys me hours of peace and quiet, which is invaluable. On top of that, they offer good nutrition!
Less Mess, More Fun:
I appreciate that these bones are relatively neat. They don't leave greasy residue all over the carpet like some marrow bones, and the durable exterior means minimal splintering (though, as with any bone, supervision is required). They satisfy my dog's natural chewing instinct while promoting dental health by scraping against his teeth as he works the chew.
Final Verdict:
If you have an aggressive chewer who needs a serious, long-lasting treat that is both entertaining and structurally sound, look no further. These stuffed bones deliver on their promise and are now a staple in our dog treat rotation!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 4, 2025
★★★★★ 5
Still Going Strong Months Later
Flavor Name: Bacon, Size: 1 Count (Pack of 1)
These stuffed chew bones have been amazing for my dogs. Even months later, they’re still happily chewing on them, and that says a lot since they’re aggressive chewers. The bacon and cheese filling keeps them interested, and the bones themselves are durable enough to handle their chewing without falling apart.
After all this time, the chews are still holding up and my dogs love them every time. They keep my dogs busy, help with dental care, and are definitely worth having on hand for large dogs who love to chew. Durable, tasty, and long-lasting—can’t ask for more.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 10, 2026
★★★★★ 5
Long lasting
Flavor Name: Bacon, Size: 1 Count (Pack of 1)
These are the longest lasting bones I have ever purchased. But if you don't want a heavy bone that makes noise when dropped this is not for you. They go sliding across my floor as they are being tossed around and played with. But they love them and they have lasted for months. I am glad they are not as expensive as others. To many things are over priced. Dogs love them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 14, 2026
★★★★★ 4
Arrived on time and as described
Flavor Name: Bacon, Size: 1 Count (Pack of 1)
It is perfect for my 120 lb dog. He did give up after 6 hours of trying to get the “stuffing” out. The bone held up to his chewing. He loved it!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 14, 2026
recommand products
Dinghy - blue
89.00
Weld Off-Road Ridge 20x9 - 8x170 BP - ET0 - 125.1mm CB - Satin Gunmetal Wheel (Black Ring)
220.50
EBC 99-02 Noble M12 2.6 Twin Turbo Yellowstuff Rear Brake Pads
183.99
Raxiom 07-23 Jeep Wrangler JK & JL 20-23 Jeep Gladiator JT Axial Series LED Fog Lights w/ Halo
69.99
Rooster Garden Art
120.00