Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 28 - Sep 2
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Calprotectin Recombinant rabbit mAb (SDT-049-44)Product Specification Host Rabbit Antigen Calprotectin Synonyms Protein S100 A8, Calgranulin A, MRP 8, S100 calcium binding protein A8 Immunogen Recombinant Protein Location Secreted Accession P05109 Clone Number SDT 049 44 Antibody Type Rabbit mAb Application WB, IHC P, IP Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 1mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage
Product Specification
| Host | Rabbit |
| Antigen | Calprotectin |
| Synonyms | Protein S100-A8, Calgranulin-A, MRP-8, S100 calcium-binding protein A8 |
| Immunogen | Recombinant Protein |
| Location | Secreted |
| Accession | P05109 |
| Clone Number | SDT-049-44 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, IP |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.1mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:3200 | null |
| WB | 1:200 | null |
| IP | 1:25 | null |
Background
Calprotectin is a complex of the mammalian proteins S100A8 and S100A9. The proteins exist as homodimers but preferentially exist as S100A8/A9 heterodimers or heterotetramers (calprotectin) with antimicrobial, proinflammatory and prothrombotic properties. In the presence of calcium, calprotectin is capable of sequestering the transition metals iron, manganese and zinc via chelation. This metal sequestration affords the complex antimicrobial properties. Calprotectin is the only known antimicrobial manganese sequestration protein complex. Calprotectin comprises as much as 60% of the soluble protein content of the cytosol of a neutrophil, and it is secreted by an unknown mechanism during inflammation Faecal calprotectin has been used to detect intestinal inflammation (colitis or enteritis) and can serve as a biomarker for inflammatory bowel diseases. Blood based calprotectin (in serum and plasma) is used in diagnostics of multiple inflammatory diseases, including autoimmune diseases, like arthritis, and severe infections including sepsis.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.1 ★★★★★
Based on 18 reviews
Sort
Product Reviews
★★★★★ 1
Don’t purchase
Falls apart in little pieces dogs can choke on
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 2, 2026
★★★★★ 5
THE KRINKLE
Ok my dogs are going nuts... krinkles every where... save me, please. Lol
Honestly they love these and you get 3 for around 8 bucks. Its hard to beat. The feel flimsy but they are holding up pretty well.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 17, 2025
★★★★★ 5
My dog loves the toy.
Color: Grey
My little dog loves the puzzle toys. She doesn't really like the treats I got. I'll get better ones.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 11, 2026
★★★★★ 5
Keep my dogs occupied
Color: Grey
Great for the dogs. Challenging and makes them work at it but not so hard they can’t eventually figure it out.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 17, 2026
★★★★★ 3
Too easy for my Lab
Color: Blue
My lab figured this out in 30 seconds. I was hoping it would be a bit more challenging for him. Thankfully, it is challenging enough for my bunny!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 28, 2026