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Description
TSLP His Tag Protein, HumanProduct Specification Species Human Synonyms thymic stromal lymphopoietin Accession Q969D9 1 Amino Acid Sequence Tyr29 Gln159 with His Tag at the C Terminus Expression System HEK293 Molecular Weight 9 14&18 27kDa (Reducing) Purity 95% by SDS PAGE & > 95% SEC HPLC Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized powder Storage Buffer PBS, PH7. 4, 5% trehalose Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in
Product Specification
| Species | Human |
| Synonyms | thymic stromal lymphopoietin |
| Accession | Q969D9-1 |
| Amino Acid Sequence | Tyr29-Gln159 with His Tag at the C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 9-14&18-27kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & > 95% SEC-HPLC |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1.Kui L, Huang J, Wang G, Zhao J, Wang S, Qin X, Liu L, Hu J, Chen L, Wang X, Li Q, Zhao Y, Tang Y, Xiong K, Zhan S, Ding H, Wang J, Cai H, Zhang Q, Zi X, Deng Q, Gao L, Wang X, Zou C, Yang H, Xiao Y, Yang B, Leng B, Zhang L, Hu G. Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice. Front Immunol. 2025 Oct 22;16:1667195. |
Background
Thymic stromal lymphopoietin (TSLP) is a cytokine secreted by epithelial cells, encoded by a gene that produces a 159-amino acid precursor protein. This protein plays a dual regulatory role in the immune system: on one hand, it promotes type 2 T-helper cell immune responses by activating dendritic cells and directly acts on immune cells such as basophils, driving the development of allergic diseases like atopic dermatitis and asthma; on the other hand, it is involved in maintaining intestinal homeostasis and central immune tolerance. Due to its central role in allergic diseases, TSLP has become an important therapeutic target for conditions such as atopic dermatitis and asthma.
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