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Description
CD19 Recombinant Rabbit mAb (Cy5 Conjugate) (S-164-41)Product Specification Host Rabbit Antigen CD19 Synonyms B lymphocyte antigen CD19, LE CD19, B lymphocyte surface antigen B4, Differentiation antigen CD19, T cell surface antigen Leu 12 Immunogen Recombinant Protein Location Cell membrane Accession P15391 Clone Number S 164 41 Antibody Type Recombinant mAb Isotype IgG Application ICC, FCM Reactivity Hu Purification Protein A Concentration 1. 3 mg ml Conjugation Cy5 Physical Appearance Liquid Storage
Product Specification
| Host | Rabbit |
| Antigen | CD19 |
| Synonyms | B-lymphocyte antigen CD19, LE-CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12 |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | P15391 |
| Clone Number | S-164-41 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | ICC, FCM |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 1.3 mg/ml |
| Conjugation | Cy5 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 0.1% BSA, 0.01% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| ICC | 1:500 | |
| FCM | 1:130 |
Background
The CD19 antigen plays an important role in clinical oncology. In normal cells, it is the most ubiquitously expressed protein in the B lymphocyte lineage. CD19 expression is induced at the point of B lineage commitment during the differentiation of the hematopoietic stem cell, and its expression continues through preB and mature B cell differentiation until it is finally down-regulated during terminal differentiation into plasma cells. CD19 expression is maintained in B-lineage cells that have undergone neoplastic transformation, and therefore CD19 is useful in diagnosis of leukemias and lymphomas using monoclonal antibodies (mAbs) and flow cytometry [PMID: 8528044].
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