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Description
OPN1SW Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen OPN1SW Synonyms Short wave sensitive opsin 1; Blue cone photoreceptor pigment; Blue sensitive opsin (BOP); BCP Immunogen Synthetic Peptide Location Cell membrane, Cytoplasm Accession P03999 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P, IF Reactivity Hu, Ms, Rt Positive Sample Human retina, mouse retina, rat retina Predicted Reactivity Cz, Mk Purification Immunogen Affinity Concentration
Product Specification
| Host | Rabbit |
| Antigen | OPN1SW |
| Synonyms | Short-wave-sensitive opsin 1; Blue cone photoreceptor pigment; Blue-sensitive opsin (BOP); BCP |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane, Cytoplasm |
| Accession | P03999 |
| Antibody Type | Polyclonal antibody |
| Isotype | IgG |
| Application | WB, IHC-P, IF |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | Human retina, mouse retina, rat retina |
| Predicted Reactivity | Cz, Mk |
| Purification | Immunogen Affinity |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Ms, Rt |
| IHC-P | 1:500 | Hu, Ms, Rt |
| IF | 1:500 | Hu, Rt |
Background
OPN1SW, also known as short-wave-sensitive opsin 1 or blue-sensitive opsin, is a protein encoded by the OPN1SW gene in humans. This protein is a type of opsin pigment found in the photoreceptor cells of the retina and is crucial for normal color vision, specifically mediating the perception of blue light. It is a G-protein coupled receptor that initiates the visual transduction cascade by converting light into electrochemical signals. The OPN1SW gene is located on chromosome 7q32.1 and is conserved across several species. Defects in this gene can lead to tritan color blindness, a condition where individuals have impaired blue-yellow color vision.
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