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Description
SARS-CoV-2 Nucleocapsid protein , His tagProduct Specification Species SARS CoV 2 Accession P0DTC9 Research Area SARS CoV 2 Amino Acid Sequence Protein sequence(P0DTC9, Met1 Ala419, with C 10*His)
Product Specification
| Species | SARS-CoV-2 |
| Accession | P0DTC9 |
| Research Area | SARS-CoV-2 |
| Amino Acid Sequence | Protein sequence(P0DTC9, Met1-Ala419, with C-10*His) |
| Expression System | E.coli |
| Molecular Weight | Theoretical: 47.3kDa Actual: 50kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, 1mM DTT, pH7.4. Normally trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute no more than 1mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2)[2] is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic.The nucleocapsid (N) protein is a protein that packages the coronaviruses to form ribonucleoprotein structures enclosed within the viral capsid. In addition to its interactions with RNA, N forms protein-protein interactions with the coronavirus membrane protein (M) during the process of viral assembly. N also has additional functions in manipulating the cell cycle of the host cell. The N protein is highly immunogenic and antibodies to N are found in patients recovered from SARS and Covid-19.
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