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Description
ARNT Recombinant Rabbit mAb (S-2263-43)Product Specification Host Rabbit Antigen ARNT Synonyms Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix loop helix protein 2 (bHLHe2); Dioxin receptor; nuclear translocator; Hypoxia inducible factor 1 beta (HIF 1 beta; HIF1 beta); BHLHE2 Immunogen Recombinant Protein Location Nucleus Accession P27540 Clone Number S 2263 43 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu, Ms, Rt Positive
Product Specification
| Host | Rabbit |
| Antigen | ARNT |
| Synonyms | Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2 (bHLHe2); Dioxin receptor; nuclear translocator; Hypoxia-inducible factor 1-beta (HIF-1-beta; HIF1-beta); BHLHE2 |
| Immunogen | Recombinant Protein |
| Location | Nucleus |
| Accession | P27540 |
| Clone Number | S-2263-43 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | HepG2, MDA-MB-231, MCF7, HeLa, 293T, NIH/3T3, RAW264.7, PC-12 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:10000 | Hu, Ms, Rt |
| ICC | 1:500 | Hu |
Background
ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator) protein is a crucial transcription factor involved in various cellular processes. It forms heterodimers with other proteins such as the aryl hydrocarbon receptor (AhR), playing a key role in the regulation of gene expression in response to environmental toxins and endogenous signals. ARNT is essential for the proper functioning of the AhR pathway, which is involved in xenobiotic metabolism, cell differentiation, and immune response modulation. Additionally, ARNT has been implicated in developmental processes and maintaining cellular homeostasis. Dysregulation of ARNT function has been associated with several pathological conditions, highlighting its importance in both normal physiology and disease.
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