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Description
PCSK9 His Tag Protein, MouseProduct Specification Species Mouse Synonyms PCSK9, FH3, PC9, FHCL3 Accession Q80W65 Amino Acid Sequence Gln35 Gln694, with C terminal 10* His Tag
Product Specification
| Species | Mouse |
| Synonyms | PCSK9, FH3, PC9, FHCL3 |
| Accession | Q80W65 |
| Amino Acid Sequence | Gln35-Gln694, with C-terminal 10* His Tag QDEDGDYEELMLALPSQEDGLADEAAHVATATFRRCSKEAWRLPGTYIVVLMEETQRLQIEQTAHRLQTRAARRGYVIKVLHIFYDLFPGFLVKMSSDLLGLALKLPHVEYIEEDSFVFAQSIPWNLERIIPAWHQTEEDRSPDGSSQVEVYLLDTSIQGAHREIEGRVTITDFNSVPEEDGTRFHRQASKCDSHGTHLAGVVSGRDAGVAKGTSLHSLRVLNCQGKGTVSGTLIGLEFIRKSQLIQPSGPLVVLLPLAGGYSRILNAACRHLARTGVVLVAAAGNFRDDACLYSPASAPEVITVGATNAQDQPVTLGTLGTNFGRCVDLFAPGKDIIGASSDCSTCFMSQSGTSQAAAHVAGIVARMLSREPTLTLAELRQRLIHFSTKDVINMAWFPEDQQVLTPNLVATLPPSTHETGGQLLCRTVWSAHSGPTRTATATARCAPEEELLSCSSFSRSGRRRGDWIEAIGGQQVCKALNAFGGEGVYAVARCCLVPRANCSIHNTPAARAGLETHVHCHQKDHVLTGCSFHWEVEDLSVRRQPALRSRRQPGQCVGHQAASVYASCCHAPGLECKIKEHGISGPSEQVTVACEAGWTLTGCNVLPGASLTLGAYSVDNLCVARVHDTARADRTSGEATVAAAICCRSRPSAKASWVQGGGSGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 60-68kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Jaén R I. et al. (2022) Functional Crosstalk between PCSK9 Internalization and Pro-Inflammatory Activation in Human Macrophages: Role of Reactive Oxygen Species Release. Int J Mol Sci. 23(16): 9114. |
Background
PCSK9 (proprotein convertase subtilisin-kexin type 9) is a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. PCSK9 undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism.
Atherosclerosis is a cardiovascular disease caused mainly by dyslipidemia and is characterized by the formation of an atheroma plaque and chronic inflammation. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protease that induces the degradation of the LDL receptor (LDLR), which contributes to increased levels of LDL cholesterol and the progress of atherosclerosis.
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4.4 ★★★★★
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Product Reviews
★★★★★ 5
5 star 🌟 would recommend
Color: BCMY
Amazing love the colors would buy again
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Reviewed in the United States on March 21, 2026
★★★★★ 4
Great color, not easy to refill
Color: BCMY
Love this ink, but I do wish that it was easier to fill. I have to use a syringe to refill my ink... I'm using an epson ET 16600.
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Reviewed in the United States on January 3, 2026
★★★★★ 5
Ink
Color: BCMY
This is my 4th order this ink is top tier and recommended.
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Reviewed in the United States on April 23, 2026
★★★★★ 5
Lo recomiendo
Color: BCMY
De lo mejor
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Reviewed in the United States on April 29, 2026
★★★★★ 5
⭐️⭐️⭐️⭐️⭐️ Easy to use and produces vibrant prints
This Hiipoo sublimation ink has been a fantastic upgrade for my EcoTank printer. The autofill bottles fit perfectly into the ink tanks - no syringes, no mess, and no wasted ink. Refilling is quick and hassle-free, which makes the whole process so much easier.
The print quality is excellent. Colors come out bright, vivid, and crisp with great saturation and no fading. It transfers beautifully onto mugs, T-shirts, and tumblers, drying fast without smudges. I really appreciate that it works ICC-free, yet still delivers professional results.
The ink is certified and feels reliable, and I’ve had zero clogging issues. Overall, this is a high-quality, easy-to-use sublimation ink that’s perfect for both hobby projects and small business use. Definitely recommend for anyone doing heat transfer printing.
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Reviewed in the United States on September 15, 2025
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