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Description
Peripherin Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen Peripherin Synonyms Neurofilament 4; NEF4; PRPH1; PRPH Immunogen Recombinant Protein Location Cytoplasm, Cytoskeleton Accession P41219 Antibody Type Polyclonal antibody Isotype IgG Application WB Reactivity Ms, Rt Positive Sample Neuro a, mouse colon, PC 12 Purification Immunogen Affinity Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA,
Product Specification
| Host | Rabbit |
| Antigen | Peripherin |
| Synonyms | Neurofilament 4; NEF4; PRPH1; PRPH |
| Immunogen | Recombinant Protein |
| Location | Cytoplasm, Cytoskeleton |
| Accession | P41219 |
| Antibody Type | Polyclonal antibody |
| Isotype | IgG |
| Application | WB |
| Reactivity | Ms, Rt |
| Positive Sample | Neuro-a, mouse colon, PC-12 |
| Purification | Immunogen Affinity |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 | Ms, Rt |
Background
Peripherin is a 57 kDa type III intermediate filament (IF) protein selectively expressed in the peripheral and enteric nervous systems, where it co-assembles with other IF subunits to form a dynamic scaffold that maintains neuronal shape, supports axonal outgrowth during development and regeneration, and provides resilience against mechanical stress; its expression is markedly up-regulated after axonal injury, making it a widely used marker of neuroplasticity, and pathogenic mutations or deranged aggregation of peripherin has been implicated in motor-neuron degenerative diseases such as amyotrophic lateral sclerosis.
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