Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 25 - Aug 30
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Rat Anti-Mouse CD170 Antibody (S-R691)Product Specification Host Rat Antigen CD170 Synonyms Sialic acid binding Ig like lectin 5; Siglec 5; Sialic acid binding Ig like lectin F (Siglec F; mSiglec F); Siglecf; Siglec5 Location Membrane Accession Q920G3 Clone Number S R691 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse bone marrow Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer
Product Specification
| Host | Rat |
| Antigen | CD170 |
| Synonyms | Sialic acid-binding Ig-like lectin 5; Siglec-5; Sialic acid-binding Ig-like lectin F (Siglec-F; mSiglec-F); Siglecf; Siglec5 |
| Location | Membrane |
| Accession | Q920G3 |
| Clone Number | S-R691 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse bone marrow |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 1:2000 | Ms |
Background
CD170, also known as Siglec-5 or OBBP2, is a type I transmembrane glycoprotein and a member of the sialic acid-binding Ig-like lectin (Siglec) family. It is expressed on various immune cells, including monocytes, neutrophils, macrophages, and dendritic cells. This molecule is characterized by its ability to bind sialic acids, which are often found on the surface of cells. It contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain, which is involved in intracellular signaling and can inhibit the activation of immune cells. CD170 is involved in mediating sialic acid-dependent cell adhesion and plays a role in immune regulation. In addition, it has been implicated in immune evasion by certain pathogens, such as Group B Streptococcus.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy