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Description
CREB Recombinant Rabbit mAb (S-747-60)Product Specification Host Rabbit Synonyms Cyclic AMP responsive element binding protein 1; CREB 1; cAMP responsive element binding protein 1; CREB1 Immunogen Synthetic Peptide Location Nucleus Accession P16220 1 Clone Number S 747 60 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM, ChIP Reactivity Hu, Ms, Rt Predicted Reactivity Bv Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance
Product Specification
| Host | Rabbit |
| Synonyms | Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1; CREB1 |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | P16220-1 |
| Clone Number | S-747-60 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM, ChIP |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Bv |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:2000 | |
| ICC | 1:500 | |
| ICFCM | 1:50 | |
| ChIP | 1:20-1:50 |
Background
CAMP responsive element binding protein 1, also known as CREB-1, is a protein that in humans is encoded by the CREB1 gene. This protein is a CREB transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.
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