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Description
Alexa Fluor 647-Labeled CD20 Flag&His Tag Full Length Protein, Human (Detergent)Product Specification Species Human Synonyms B lymphocyte surface antigen B1MS4A1B lymphocyte antigen CD20Membrane Spanning 4 Domains A1Leukocyte Surface Antigen Leu 16CD20 AntigenCD20Bp35Membrane Spanning 4 Domains Subfamily A Member 1CD20 ReceptorLEU 16CVID5MS4A2B1S7Antigens CD20Membrane Spanning 4 Domains Subfamily A Member 1B Lymphocyte Cell Surface Antigen B1 Accession P11836 Amino Acid Sequence Full length, with Flag tag at N Terminus, and His
Product Specification
| Species | Human |
| Synonyms | B-lymphocyte surface antigen B1，MS4A1，B-lymphocyte antigen CD20，Membrane Spanning 4-Domains A1，Leukocyte Surface Antigen Leu-16，CD20 Antigen，CD20，Bp35，Membrane-Spanning 4-Domains Subfamily A Member 1，CD20 Receptor，LEU-16，CVID5，MS4A2，B1，S7，Antigens， CD20，Membrane-Spanning 4-Domains， Subfamily A， Member 1，B-Lymphocyte Cell-Surface Antigen B1 |
| Accession | P11836 |
| Amino Acid Sequence | Full length, with Flag tag at N-Terminus, and His tag at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 35.4 kDa |
| Conjugation | Alexa Fluor® 647 |
| Tag | His Tag, Flag Tag |
| Physical Appearance | Liquid |
| Storage Buffer | 25mM Hepes,150mM NaCl,0.02%DDM |
| Stability & Storage |
· 16 months from date of receipt stored at -80℃. |
| Reference | 1. Rougé L, Chiang N, Steffek M, et al. Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab[J]. Science, 2020, 367(6483): 1224-1230. |
Background
CD20 is a 33-37 kDa non-glycosylated protein present on the surface of normal and malignant B lymphocytes and is a member of the MS4A (membrane-spanning 4-domain family A) protein family. The CD20 protein comprises four hydrophobic transmembrane domains, one intracellular domain, and two extracellular domains (a large loop and a small loop), with both the N- and C-termini located within the cytosol. CD20 is associated with several key molecules, including the major histocompatibility complex class II (MHCII), CD40 molecule, B-cell receptor (BCR), and the C-terminal src kinase-binding protein (CBP). CBP interacts with Src kinases such as LYN, FYN, and LCK.A deficiency in CD20 has been shown to result in a reduced number of circulating memory B cells, decreased isotype switching of immunoglobulins (Ig), and lower IgG antibody levels. It is also linked to various pathophysiological diseases and disorders.CD20 plays a crucial role in multiple physiological processes and is thus a promising therapeutic target. The CD20 protein product has the potential to enhance drug discovery efforts in related fields.
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4.7 ★★★★★
Based on 17 reviews
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Product Reviews
★★★★★ 5
Easy to configure. So helpful!
Color: Clear, Color: Clear
My house has old bathroom cabinets that are too narrow for most organizers I have found. These organizers come in different sizes so I can mix and match the pieces to fit the drawers and items I have to store.
I have filled two drawers with these and still have more containers to use. These are truly the tool for the job. They are sturdy, stable and I thought I would have trouble with them moving around but they stay in place while maintaining their versatility. If I need to switch out stuff, I just reconfigure the drawer. No assembly required.
One of my most favorite simple purchases. I can’t believe I have lived without these simple but helpful organizers!
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Reviewed in the United States on March 8, 2026
★★★★★ 5
Great for lip gloss. Headbands. Little toys and trinkets for preteen
Color: Lilac
This set is great! I love the colors, and my daughter is obsessed with anything purple — light purple, dark purple, all of it 💜. She uses these for all her little trinkets like keychains, Q-tips, headbands, braces, hand sanitizers, little toys, and lip glosses. They’re easy to use, easy to clean, and great quality. She’s had them for a few months now and they’ve held up really well Different sizes. They like up for accessibility
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Reviewed in the United States on May 28, 2026
★★★★★ 1
Not sturdy, practical, or worth the price.
Style: TREE
Very cheap, unsteady.
Thin material, feels like it will snap with very little pressure. Does not stand up well, so when I place jewelry on it (2 very small pendants on thin solver chains), it tips over, making it not very functional or practical. It also is short, so even short chains fall onto the table (no tray below). I could have gotten a better one at Five Below for less. Really disappointed.
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Reviewed in the United States on January 16, 2026
★★★★★ 5
Happy Birthday Girl
Style: TREE
Bought this as a birthday present and added jewelry to it and it was a huge hit! Perfect for what we wanted and an amazing price!
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Reviewed in the United States on April 22, 2026
★★★★★ 1
Too light weight!
Style: TREE
Very light weight. Fall over constantly. Had to use double sided tape to keep it upright!
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Reviewed in the United States on April 28, 2026