SKU: 82173234791

IL-17 RA Protein, Human

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Description

IL-17 RA Protein, HumanProduct Specification Species Human Synonyms Interleukin 17RA Accession Q96F46 Amino Acid Sequence Leu33 Trp320, with C terminal 8*His LRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTPEPIPDYMPLWGGGSHHHHHHHH Expression System

Product Specification


Species Human
Synonyms Interleukin 17RA
Accession Q96F46
Amino Acid Sequence

Leu33-Trp320, with C-terminal 8*His LRLLDHRALVCSQPGLNCTVKNSTCLDDSWIHPRNLTPSSPKDLQIQLHFAHTQQGDLFPVAHIEWTLQTDASILYLEGAELSVLQLNTNERLCVRFEFLSKLRHHHRRWRFTFSHFVVDPDQEYEVTVHHLPKPIPDGDPNHQSKNFLVPDCEHARMKVTTPCMSSGSLWDPNITVETLEAHQLRVSFTLWNESTHYQILLTSFPHMENHSCFEHMHHIPAPRPEEFHQRSNVTLTLRNLKGCCRHQVQIQPFFSSCLNDCLRHSATVSCPEMPDTPEPIPDYMPLWGGGSHHHHHHHH

Expression System CHO
Molecular Weight

43-60kDa (Reducing)

Purity

>95% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, pH7.4

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.

· 3 months, -20 to -80℃ under sterile conditions after reconstitution.

· 1 week, 2 to 8℃ under sterile conditions after reconstitution.

· Please avoid repeated freeze-thaw cycles.

Background

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

The paradigm of psoriasis as a Th17-driven disease has evolved in the last years towards a much deeper knowledge of the complex pathways, mechanisms, cells, and messengers involved, highlighting the crucial role played by the IL-17 family of cytokines. All IL-17 isoforms signal through IL-17R. Five subunits of IL-17R have been described to date, which couple to form a homo- or hetero-receptor complex. Characteristically, IL-17RA is a common subunit in all hetero-receptors. IL-17RA has unique structural-containing a SEFIR/TILL domain-and functional-requiring ACT-1 for signaling-properties, enabling Th17 cells to act as a bridge between innate and adaptive immune cells.

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SKU: 82173234791

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YakooziJacuzzi
Charlottesville, US
★★★★★ 1
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My pack arrived late AND was already opened. Considering this is food, I'm not sure if this is even safe to eat. A real shame since I was really looking forward to having some good biltong.
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Reviewed in the United States on September 9, 2025
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Albertus
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★★★★★ 5
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Good
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Reviewed in the United States on April 24, 2026
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Michael
Carnegie, US
★★★★★ 5
Hands down my favorite.
Hands down, amazing. Chewy, not overly spiced, lean, and very delicious.
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Reviewed in the United States on January 23, 2026
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Kurt W. Schsuter
Fort Morgan, US
★★★★★ 3
GRISTLE
These are large pieces compared to their other products. So you know, these, specifically my order, has so much connective tissue, that once you're done separating the meat from the gristle, the larger portion is gristle. Flavor is great as usual though.
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Reviewed in the United States on February 12, 2026
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Larry Susman
Charlottesville, US
★★★★★ 5
One of the best
Great biltong. Beef quality was great and the taste to die for. Thanks
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Reviewed in the United States on June 8, 2025

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