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Description
S100A8 (MRP8) Recombinant Rabbit mAb (SDT-059-28)Product Specification Host Rabbit Antigen S100A8 (MRP8) Synonyms Protein S100 A8, CFAG Immunogen Synthetic Peptide Location Cytoplasm, Secreted, Cell membrane Accession P05109 Clone Number SDT 059 28 Antibody Type Rabbit mAb Application WB, IHC P, ICC, IP Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05 %BSA, 0. 03% Proclin 300 Stability & Storage 12 months from
Product Specification
| Host | Rabbit |
| Antigen | S100A8 (MRP8) |
| Synonyms | Protein S100-A8, CFAG |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Secreted, Cell membrane |
| Accession | P05109 |
| Clone Number | SDT-059-28 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC, IP |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05 %BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:2000 | |
| IP | 1:50 | |
| ICC | 1:500 |
Background
S100A8 (MRP8) is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.
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