SKU: 83382905498

Biotinylated CD3E&CD3D Fc, His, Avi tag&Fc, Flag, Avi tag Heterodimer Protein, Human

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Description

Biotinylated CD3E&CD3D Fc, His, Avi tag&Fc, Flag, Avi tag Heterodimer Protein, HumanProduct Specification Species Human Synonyms CD3 epsilon&CD3 delta, CD3E & CD3D, CD3 delta & CD3 epsilon Accession P07766 1P04234 1 Amino Acid Sequence Asp 23 Asp 126 (CD3E) with hIgG1 Fc Tag at the C Terminus, followed by polyhistidine tag and Avi tag Phe 22 Ala 105 (CD3D) with hIgG1 Fc Tag at the C Terminus, followed by Flag tag and Avi tag Expression System HEK293 Molecular Weight 43 55kDa (Reducing) Purity 95% by SDS PAGE Conjugation Unconjugated

Product Specification


Species Human
Synonyms CD3 epsilon&CD3 delta, CD3E & CD3D, CD3 delta & CD3 epsilon
Accession P07766-1、P04234-1
Amino Acid Sequence

Asp 23 - Asp 126 (CD3E) with hIgG1 Fc Tag at the C-Terminus, followed by polyhistidine tag and Avi tag
Phe 22 - Ala 105 (CD3D) with hIgG1 Fc Tag at the C-Terminus, followed by Flag tag and Avi tag

Expression System HEK293
Molecular Weight

43-55kDa (Reducing)

Purity >95% by SDS-PAGE
Conjugation Unconjugated
Tag Avi Tag, His Tag, Flag Tag, Human IgG1 Fc
Physical Appearance Lyophilized powder
Storage Buffer

PBS, PH7.4, 5% trehalose

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Reference

1. Tuning TCR complex recruitment to the T cell antigen coupler (TAC) enhances TAC-T cell function. Sci Rep. 2025 Feb 25;15(1):6769.
2. Gedeon P C , Schaller T H , Chitneni S K , et al. A rationally designed fully human EGFRvIII:CD3-targeted bispecific antibody redirects human T cells to treat patient-derived intracerebral malignant glioma.[J]. Clinical Cancer Research, 2018:clincanres.0126.2017.

Background

T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
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SKU: 83382905498

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4.5 ★★★★★
Based on 11 reviews
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Verified Purchase
rosa arellano
Louisville, US
★★★★★ 5
I have arthritis and it works really well and very easy to use it came fully charged that was nice.
Very nice ;-)
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Reviewed in the United States on June 7, 2026
T
Verified Purchase
Tim P.
Charlottesville, US
★★★★★ 5
Easy to use! No more hand cranking.
If you like the ease of an electric can opener, but don’t have room to store it or don’t want to drag it out when you need to use it, this is for you. I like a handheld can opener, but would get so frustrated trying to use it and turn the handle. This can opener is amazing and so easy to use. Just attach to can and push a button. It starts turning on its own and when it is done it stops. You lift it up and the lid comes off cleanly. It is rechargeable so need to worry about batteries. It tucks away in a drawer nicely. I bought my mom one too. She has arthritis in her hands so thought this would be perfect for her.
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Reviewed in the United States on January 10, 2026
A
Verified Purchase
Albert C.
Battle Creek, US
★★★★★ 5
Smooth edges better than twisting
Works a lot better than the crank style and the counter top electric and you can use the lid to reseal the can if you don't use the whole thing.
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Reviewed in the United States on June 3, 2026
A
Verified Purchase
Amazon Customer
Battle Creek, US
★★★★★ 2
Worked for only 4 months. Now produces metal shards. Dangerous
Pros: Can be used with one hand. I bought this to have after surgery that left me without use of one arm for a few months. The light blinks when you need to charge it. Only needs a 2-3 min charge for enough juice to open a can. Cons: IT QUIT CUTTING CORRECTLY AFTER 4 MONTHS. I now have to use both hands to hold it in place to get it to latch on to the can. It also requires a few rotations around the top to cut through the seal, resulting in METAL SHARDS! The metal shards are super sharp and almost invisible. I stabbed myself with one enough to draw blood. This is dangerous as the metal could fall into the food when pouring from the can.
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Reviewed in the United States on January 10, 2026
C
Verified Purchase
Catibbetts
Omaha, US
★★★★★ 1
Can opener
This product does not work well! It actually doesn't work at all!! Will not cut thru can lids at all. Very disappointing to say the least. I purchased to make things easier only to be left not being able to open dinner 😕. Would not recommend to anyone!!!
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Reviewed in the United States on May 15, 2026

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